Dipartimento di Ambiente e Connessa Prevenzione Primaria, Istituto Superiore di Sanità, Rome, Italy. E-mail:
Ann Ist Super Sanita. 2014;50(2):111-8. doi: 10.4415/ANN_14_02_02.
Amphibolic fibres with fluoro-edenitic composition characterize Biancavilla soil, including the major quarry from which building materials have been extensively extracted. These fibres induce mesothelioma in experimental animals and their in vitro biological action is similar to that of crocidolite.
Malignant mesothelioma case series and incidence were examined to evaluate the disease burden on Biancavilla inhabitants.
The incidence of pleural mesothelioma in Biancavilla is steadily higher than in the Sicilian Region, risk estimates are more elevated in women than in men, the most affected age class is constituted by subjects aged less than 50.
Environmental exposure to fibres with fluoro-edenitic composition appears to be causally related to the elevated mesothelioma occurrence in Biancavilla. In this frame, environmental clean-up is the main goal to be pursued in public health terms. A contribution of scientific research to public health decision making with respect to priority setting for environmental clean-up can derive from some further selected epidemiological investigations.
具有氟-镁电气石成分的 Amphibolic 纤维是 Biancavilla 土壤的特征，包括主要的采石场，建筑材料就是从那里大量提取的。这些纤维在实验动物中诱发间皮瘤，其体外生物学作用类似于青石棉。
研究了恶性间皮瘤病例系列和发病率，以评估 Biancavilla 居民的疾病负担。
Biancavilla 的胸膜间皮瘤发病率一直高于西西里地区，女性的风险估计值高于男性，受影响最大的年龄组是年龄小于 50 岁的人群。
环境中接触具有氟-镁电气石成分的纤维似乎与 Biancavilla 间皮瘤发病率升高有关。在这方面，环境清理是公共卫生方面需要追求的主要目标。科学研究可以为公共卫生决策做出贡献，为环境清理的优先事项设定提供依据。
