Topel Seda Demirel, Cin Gunseli Turgut, Akkaya Engin U
Department of Chemistry, Faculty of Science, Akdeniz University, 07058, Antalya, Turkey.
Chem Commun (Camb). 2014 Aug 18;50(64):8896-9. doi: 10.1039/c4cc03387f.
Orthogonal dimers of Bodipy were recently shown to be efficient generators of singlet oxygen. However, these dyes require green light for excitation, which would be very quickly attenuated inside the mammalian tissues. We now demonstrate that when these dyes are covalently attached to UCNPs, near IR irradiation results in very efficient generation of singlet oxygen.
近来研究表明，硼二吡咯（Bodipy）的正交二聚体是单线态氧的高效产生剂。然而，这些染料需要绿光激发，而绿光在哺乳动物组织内会很快衰减。我们现在证明，当这些染料共价连接到上转换纳米粒子（UCNPs）上时，近红外辐射会导致单线态氧的高效产生。
