Department of Pharmacy Practice, Harrison School of Pharmacy, Auburn University, Auburn, AL.
Adv Chronic Kidney Dis. 2014 Jul;21(4):349-54. doi: 10.1053/j.ackd.2014.03.014.
The kidney plays a major role in pharmacokinetics and pharmacodynamics of drugs; therefore, medication errors can result from failure to properly adjust medications in patients with CKD. It is the responsibility of all health-care providers to work collectively when reviewing medications, initiating new medications, and adjusting doses of current medications. Awareness of appropriate dosing recommendations can significantly decrease medication error-associated morbidity, mortality, and cost.
肾脏在药物的药代动力学和药效动力学中起着重要作用；因此，未能正确调整 CKD 患者的药物可能导致用药错误。所有医疗保健提供者在审查药物、开始新药物和调整现有药物剂量时都有责任共同合作。了解适当的剂量建议可以显著降低与用药错误相关的发病率、死亡率和成本。
