大豆疏水性蛋白对外电场的响应：一种分子建模方法。

Department of Bioresource Engineering, McGill University, 21,111 Rue Lakeshore, Ste-anne-de-bellevue, QC, H9X 3V9, Canada.

Biomolecules. 2013 Feb 11;3(1):168-79. doi: 10.3390/biom3010168.

The molecular dynamic (MD) modeling approach was applied to evaluate the effect of an external electric field on soybean hydrophobic protein and surface properties. Nominal electric field strengths of 0.002 V/nm and 0.004 V/nm had no major effect on the structure and surface properties of the protein isolate but the higher electric field strength of 3 V/nm significantly affected the protein conformation and solvent accessible surface area. The response of protein isolate to various external field stresses demonstrated that it is necessary to gain insight into protein dynamics under electromagnetic fields in order to be able to develop the techniques utilizing them for food processing and other biological applications.

采用分子动力学（MD）建模方法来评估外加电场对大豆疏水性蛋白及其表面性质的影响。外加电场强度分别为 0.002 V/nm 和 0.004 V/nm 时，对蛋白质分离物的结构和表面性质没有重大影响，但 3 V/nm 的较高电场强度显著影响了蛋白质构象和溶剂可及表面积。蛋白质分离物对外界各种场应力的响应表明，有必要深入了解电磁场下的蛋白质动力学，以便能够开发利用这些技术进行食品加工和其他生物应用。