Sallard Etienne, Tallet Jessica, Thut Gregor, Deiber Marie-Pierre, Barral Jérôme
Research Group of Institute of Sport Sciences University of Lausanne (GRISSUL), University of Lausanne, Lausanne, Switzerland.
PRISSMH-LAPMA, University of Toulouse3, Toulouse, France.
Behav Brain Res. 2014 Sep 1;271:365-73. doi: 10.1016/j.bbr.2014.05.070. Epub 2014 Jun 24.
It is known that post-movement beta synchronization (PMBS) is involved both in active inhibition and in sensory reafferences processes. The aim of this study was examine the temporal and spatial dynamics of the PMBS involved during multi-limb coordination task. We investigated post-switching beta synchronization (assigned PMBS) using time-frequency and source estimations analyzes. Participants (n=17) initiated an auditory-paced bimanual tapping. After a 1,500 ms preparatory period, an imperative stimulus required to either selectively stop the left while maintaining the right unimanual tapping (Switch condition: SWIT) or to continue the bimanual tapping (Continue condition: CONT). PMBS significantly increased in SWIT compared to CONT with maximal difference within right central region in broad-band 14-30 Hz and within left central region in restricted-band 22-26 Hz. Source estimations localized these effects within right pre-frontal cortex and left parietal cortex, respectively. A negative correlation showed that participants with a low percentage of errors in SWIT had a large PMBS amplitude within right parietal and frontal cortices. This study shows for the first time simultaneous PMBS with distinct functions in different brain regions and frequency ranges. The left parietal PMBS restricted to 22-26 Hz could reflect the sensory reafferences of the right hand tapping disrupted by the switching. In contrast, the right pre-frontal PMBS in a broad-band 14-30 Hz is likely reflecting the active inhibition of the left hand stopped. Finally, correlations between behavioral performance and the magnitude of the PMBS suggest that beta oscillations can be viewed as a marker of successful active inhibition.
已知运动后β同步化（PMBS）参与主动抑制和感觉传入过程。本研究的目的是研究多肢体协调任务中PMBS的时间和空间动态。我们使用时频分析和源估计分析来研究切换后β同步化（指定为PMBS）。参与者（n = 17）开始进行听觉节奏的双手敲击。在1500毫秒的准备期后，一个命令性刺激要求要么在保持右手单手敲击的同时选择性地停止左手敲击（切换条件：SWIT），要么继续双手敲击（继续条件：CONT）。与CONT相比，SWIT中的PMBS显著增加，在宽带14 - 30 Hz的右侧中央区域和窄带22 - 26 Hz的左侧中央区域差异最大。源估计分别将这些效应定位在右侧前额叶皮层和左侧顶叶皮层内。负相关表明，在SWIT中错误百分比低的参与者在右侧顶叶和额叶皮层内具有较大的PMBS幅度。本研究首次表明在不同脑区和频率范围内同时存在具有不同功能的PMBS。局限于22 - 26 Hz的左侧顶叶PMBS可能反映了切换干扰的右手敲击的感觉传入。相反，宽带14 - 30 Hz的右侧前额叶PMBS可能反映了对停止的左手的主动抑制。最后，行为表现与PMBS幅度之间的相关性表明，β振荡可被视为成功主动抑制的标志。
