鸽腺病毒1型和鸭腺病毒2型的全基因组序列增加了禽腺病毒属内的病毒种类数量。
Complete genome sequences of pigeon adenovirus 1 and duck adenovirus 2 extend the number of species within the genus Aviadenovirus.
作者信息
Marek Ana, Kaján Győző L, Kosiol Carolin, Harrach Balázs, Schlötterer Christian, Hess Michael
机构信息
Clinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, Vetmeduni Vienna, Veterinärplatz 1, 1210 Vienna, Austria.
Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary.
出版信息
Virology. 2014 Aug;462-463:107-14. doi: 10.1016/j.virol.2014.04.033. Epub 2014 Jun 25.
Complete genomes of the first isolates of pigeon adenovirus 1 (PiAdV-1) and Muscovy duck adenovirus (duck adenovirus 2, DAdV-2) were sequenced. The PiAdV-1 genome is 45,480bp long, and has a gene organization most similar to turkey adenovirus 1. Near the left end of the genome, it lacks ORF0, ORF1A, ORF1B and ORF1C, and possesses ORF52, whereas six novel genes were found near the right end. The DAdV-2 genome is 43,734bp long, and has a gene organization similar to that of goose adenovirus 4 (GoAdV-4). It lacks ORF51, ORF1C and ORF54, and possesses ORF55A and five other novel genes. PiAdV-1 and DAdV-2 genomes contain two and one fiber genes, respectively. Genome organization, G+C content, molecular phylogeny and host type confirm the need to establish two novel species (Pigeon aviadenovirus A and Duck aviadenovirus B) within the genus Aviadenovirus. Phylogenetic data show that DAdV-2 is most closely related to GoAdV-4.
对鸽腺病毒1型（PiAdV-1）和番鸭腺病毒（鸭腺病毒2型，DAdV-2）的首批分离株的全基因组进行了测序。PiAdV-1基因组长度为45,480bp，其基因组织与火鸡腺病毒1型最为相似。在基因组左端附近，它缺少ORF0、ORF1A、ORF1B和ORF1C，但拥有ORF52，而在右端附近发现了6个新基因。DAdV-2基因组长度为43,734bp，其基因组织与鹅腺病毒4型（GoAdV-4）相似。它缺少ORF51、ORF1C和ORF54，但拥有ORF55A和其他5个新基因。PiAdV-1和DAdV-2基因组分别包含2个和1个纤维基因。基因组组织、G+C含量、分子系统发育和宿主类型证实有必要在禽腺病毒属内建立两个新种（鸽禽腺病毒A和鸭禽腺病毒B）。系统发育数据表明，DAdV-2与GoAdV-4关系最为密切。
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