Elevated anti-D titer after the administration of Rh immune globulin. A case report.

An anti-D titer of 1:16 was detected in a woman who had received 300 micrograms of Rh immune globulin as antepartum prophylaxis. It has been generally accepted that antibody titers following the administration of Rh immune globulin are less than 1:2. Although Rh immunization is always a potential cause of a titer greater than 1:4, a conservative approach is warranted in managing the patient with elevated anti-D antibody titers detected following the administration of Rh immune globulin.