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甲状腺次全切除术后罕见的复发性双侧后纵隔甲状腺肿:病例报告

An unusual recurrent bilateral posterior mediastinal goiter after subtotal thyroidectomy: Case report.

作者信息

Aziret Mehmet, Topçuoğlu Mehmet Şah, Ozçelik Cemal, Ozkaya Muharrem

机构信息

Adana Numune Training and Research Hospital Department of General Surgery, Adana and Kars State Hospital General Surgery, Turkey.

Çukurova University, Department of Cardiovascular Surgery, Adana, Turkey.

出版信息

Int J Surg Case Rep. 2014;5(8):465-8. doi: 10.1016/j.ijscr.2014.05.015. Epub 2014 Jun 6.

DOI:10.1016/j.ijscr.2014.05.015
PMID:24973529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4147647/
Abstract

INTRODUCTION

Surgical treatment of benign thyroid diseases need to be followed up closely, since recurrent thyroid nodules can be seen after subtotal thyroidectomy. Intrathoracic goiter (ITG) occurs in 10-30% of patients following subtotal thyroidectomy. In general these goiters are benign, having a malignant rate of only 2-22%. ITG grows slowly but steadily and in its process of development, it narrows the thoracic inlet by compressing the surrounding structures. Most of these can not located in the anterior mediastinum, others located in posterior retrovascular area. Bilateral posterior retrovascular goiters are very rare.

PRESENTATION OF CASE

We report a case involving a 61-year-old woman with history of gradual-onset dyspnea who was referred to us for evaluation of a large mediastinal mass. She had undergone bilateral thyroid lobectomy for a cervical goiter 10 years ago. The mass was removed successfully via median sternotomy without complication. The patient recovered well and was discharged in 1 week.

DISCUSSION

Most anterior mediastinal goiters can be resected through a transcervical approach, but if those extending beyond the aortic arch into the posterior mediastinum are better dealt with by sternotomy or lateral thoracotomy.

CONCLUSION

Bilateral recurrent posterior mediastinal and retrovascular large goiters are better resected via sternotomy rather than lateral thoracotomy. The reason for that are the possibility of injury to large vascular structures and the difficulty of their management through lateral thoracotomy when cardiopulmonary bypass needed.

摘要

引言

良性甲状腺疾病的手术治疗需要密切随访,因为甲状腺次全切除术后可见甲状腺结节复发。胸内甲状腺肿(ITG)在甲状腺次全切除术后的患者中发生率为10% - 30%。一般来说,这些甲状腺肿是良性的,恶性率仅为2% - 22%。ITG生长缓慢但稳定,在其发展过程中,会通过压迫周围结构使胸廓入口变窄。其中大多数位于前纵隔,其他位于后血管区域。双侧后血管甲状腺肿非常罕见。

病例介绍

我们报告一例病例,患者为一名61岁女性,有逐渐加重的呼吸困难病史,因评估一个大的纵隔肿块而转诊至我院。她10年前因颈部甲状腺肿接受了双侧甲状腺叶切除术。通过正中胸骨切开术成功切除肿块,无并发症。患者恢复良好,1周后出院。

讨论

大多数前纵隔甲状腺肿可通过经颈入路切除,但如果那些延伸至主动脉弓以外进入后纵隔的甲状腺肿,采用胸骨切开术或侧胸壁切开术处理更好。

结论

双侧复发性后纵隔及后血管大甲状腺肿通过胸骨切开术而非侧胸壁切开术切除更好。原因是存在损伤大血管结构的可能性,以及在需要体外循环时通过侧胸壁切开术处理这些血管的困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0ec/4147647/047de9c21fd4/gr4v5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0ec/4147647/2d9235fc6c53/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0ec/4147647/1fa1d5ae2c22/gr2v3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0ec/4147647/047de9c21fd4/gr4v5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0ec/4147647/2d9235fc6c53/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0ec/4147647/1fa1d5ae2c22/gr2v3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0ec/4147647/047de9c21fd4/gr4v5.jpg

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本文引用的文献

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Can pre-operative computed tomography predict the need for a thoracic approach for removal of retrosternal goitre?术前计算机断层扫描能否预测胸骨后甲状腺肿切除需行胸腔入路?
Int J Surg. 2013;11(3):203-8. doi: 10.1016/j.ijsu.2013.01.006. Epub 2013 Jan 23.
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Resection of a giant bilateral retrovascular intrathoracic goiter causing severe upper airway obstruction, 2 years after subtotal thyroidectomy: a case report and review of the literature.巨大双侧返流行胸腔内甲状腺肿切除术后 2 年,因严重上呼吸道梗阻再次手术:病例报告及文献复习。
J Thorac Dis. 2012 Nov;4 Suppl 1(Suppl 1):41-8. doi: 10.3978/j.issn.2072-1439.2012.s004.
3
Retrosternal goiter located in the mediastinum: surgical approach and operative difficulties.
位于纵隔的胸骨后甲状腺肿:手术入路及手术难点
Interact Cardiovasc Thorac Surg. 2012 Nov;15(5):935-7. doi: 10.1093/icvts/ivs339. Epub 2012 Aug 23.
4
Large posterior mediastinal retrosternal goiter managed by a transcervical and lateral thoracotomy approach.采用经颈部和侧胸壁切开术治疗的巨大后纵隔胸骨后甲状腺肿。
Gen Thorac Cardiovasc Surg. 2011 Jul;59(7):507-11. doi: 10.1007/s11748-010-0712-x. Epub 2011 Jul 14.
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An unusual recurrent intrathoracic goiter: Case report.一例罕见的复发性胸内甲状腺肿:病例报告。
Ear Nose Throat J. 2010 Oct;89(10):E41-2. doi: 10.1177/014556131008901008.
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Benign cervical multi-nodular goiter presenting with acute airway obstruction: a case report.良性颈部多发性结节性甲状腺肿伴急性气道梗阻:一例报告
J Med Case Rep. 2010 Aug 10;4:258. doi: 10.1186/1752-1947-4-258.
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Enormous goiter in posterior mediastinum: report of 2 cases and literature review.后纵隔巨大甲状腺肿:2例报告及文献复习
J Formos Med Assoc. 2009 Apr;108(4):337-43. doi: 10.1016/S0929-6646(09)60075-9.
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Surgical management of mediastinal goiter: risk factors for sternotomy.纵隔甲状腺肿的外科治疗:胸骨切开术的危险因素
Langenbecks Arch Surg. 2008 Sep;393(5):751-7. doi: 10.1007/s00423-008-0338-y. Epub 2008 May 17.
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