Cardiothoracic Department, St Luke's Hospital, Panorama, Thessaloniki, Greece;
J Thorac Dis. 2012 Nov;4 Suppl 1(Suppl 1):41-8. doi: 10.3978/j.issn.2072-1439.2012.s004.
The intrathoracic (or substernal) goiter is more often benign; but it can be malignant in 2-22% of patients. There is history of prior thyroid surgery in 10% to more than 30% of patients. Intrathoracic goiters cause adjacent structure compression more frequently than the cervical goiters, due to the limited space of the thoracic cage. Compression of trachea, oesophagus, vascular and neural structures may cause dyspnoea, dysphagia, superior vena cava syndrome, subclavian vein thrombosis, hoarseness, and Horner's syndrome. There is usually progressive deterioration, but acute exacerbation may occur. The presence of a thoracic goiter (>50% of the mass below the thoracic inlet) is per se an indication for resection. Tracheal compression by (cervical or thoracic) goiter is also an indication for resection; early tracheal decompression is recommended particularly in symptomatic patients. In severe respiratory distress, intubation and semi-urgent operation may be required. With early intervention, most intrathoracic goiters can be removed through a cervical approach, while tracheomalacia is avoided. We hereby present successful and uncomplicated total thyroidectomy, through a median sternotomy, of a benign, gigantic, bilateral, retrovascular, posterior mediastinal, intrathoracic goiter, encircling the trachea, and causing severe respiratory distress in a 63 year old man with history of previous subtotal thyroidectomy.
胸内(或胸骨后)甲状腺肿更常为良性;但在 2-22%的患者中可能为恶性。10%至 30%以上的患者有既往甲状腺手术史。由于胸腔的空间有限,胸内甲状腺肿比颈内甲状腺肿更常引起邻近结构的压迫。气管、食管、血管和神经结构的压迫可导致呼吸困难、吞咽困难、上腔静脉综合征、锁骨下静脉血栓形成、声音嘶哑和霍纳氏综合征。通常病情逐渐恶化,但也可能发生急性恶化。胸内甲状腺肿(肿块位于胸廓入口以下的 50%以上)本身就是切除的指征。(颈或胸)甲状腺肿压迫气管也是切除的指征;建议对有症状的患者早期进行气管减压。在严重呼吸窘迫的情况下,可能需要插管和半紧急手术。通过早期干预,大多数胸内甲状腺肿可以通过颈部入路切除,同时避免气管软化。我们在此报告一例成功且无并发症的良性、巨大、双侧、血管后、纵隔后、胸内甲状腺肿的全甲状腺切除术,该甲状腺肿环绕气管,导致一名 63 岁既往行甲状腺次全切除术的男性出现严重呼吸窘迫。