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犬第三眼睑腺肌上皮瘤

Myoepithelioma of the gland of the third eyelid in a dog.

作者信息

Bondoc A, Izawa T, Hirata S, Hasegawa T, Kuwamura M, Golbar H M, Yamate J

机构信息

Veterinary Pathology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-Ourai-Kita, Izumisano, Osaka 598-8531, Japan.

Veterinary Pathology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-Ourai-Kita, Izumisano, Osaka 598-8531, Japan.

出版信息

J Comp Pathol. 2014 Aug-Oct;151(2-3):186-9. doi: 10.1016/j.jcpa.2014.04.011. Epub 2014 Jun 25.

Abstract

A 12-year-old female miniature dachshund was presented with a tan-white, firm mass (4 × 3 × 2 cm) occupying the left medial canthus. The mass compressed and displaced the left eye dorsally, and it was surgically removed. Microscopically, the mass was composed of interlacing bundles of spindle cells with clear cytoplasm and a small number of atypical glandular epithelial cells. Immunohistochemically, the spindle cells expressed p63, α-smooth muscle actin and calponin, and were negative for cytokeratin AE1/AE3. The glandular epithelial cells expressed cytokeratin AE1/AE3. Based on these findings, this case was diagnosed as a myoepithelioma of the gland of the third eyelid.

摘要

一只12岁的雌性迷你腊肠犬因左内眦出现一个棕白色、质地坚硬的肿块(4×3×2厘米)前来就诊。该肿块将左眼向上挤压并移位,遂进行了手术切除。显微镜下,肿块由交织成束的梭形细胞组成,胞质清亮,并有少量非典型腺上皮细胞。免疫组织化学检查显示,梭形细胞表达p63、α平滑肌肌动蛋白和钙调蛋白,细胞角蛋白AE1/AE3呈阴性。腺上皮细胞表达细胞角蛋白AE1/AE3。基于这些发现,该病例被诊断为第三眼睑腺肌上皮瘤。

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