Bulum Burcu, Özçakar Zeynep Birsin, Kavaz Asli, Hüseynova Mehriban, Ekim Mesiha, Yalçinkaya Fatoş
Department of Paediatric Nephrology, Ankara University School of Medicine, Ankara, Turkey.
Acta Paediatr. 2014 Oct;103(10):e454-8. doi: 10.1111/apa.12732. Epub 2014 Jul 18.
Previous studies suggest that 6-46% of children suffer from lower urinary tract dysfunction (LUTD). This study evaluated the prevalence of LUTD in children with a urinary tract infection (UTI) and assessed the impact of standard urotherapy on patients with LUTD.
We enrolled 228 patients who were 4 years of age or older with at least one episode of UTI, together with a control group of 100 children. All the children were evaluated using the Pediatric Lower Urinary Tract Symptom Score (PLUTSS), and the intervention group were re-assessed after therapy to gauge their response.
Lower urinary tract dysfunction was detected in 134 (59%) patients. Their mean PLUTSS was 15.9 ± 5.3, and 78% of these patients had a reduced quality of life (QOL). After 5 ± 2.7 months of behavioural therapy, 105 (78%) patients with LUTD were evaluated for the second time. This showed that LUTD was ameliorated in 69% of the patients and improved in 26%, with a mean post-treatment PLUTSS of 6.6 ± 5.6. Two control group children had LUTD.
Lower urinary tract dysfunction was frequently seen in patients with UTIs, but standard urotherapy was usually successful. Most of the patients in our study with LUTD also had an impaired QOL.
先前的研究表明，6%至46%的儿童患有下尿路功能障碍（LUTD）。本研究评估了尿路感染（UTI）患儿中LUTD的患病率，并评估了标准尿流疗法对LUTD患者的影响。
我们招募了228名4岁及以上且至少有一次UTI发作的患者，以及一个由100名儿童组成的对照组。所有儿童均使用小儿下尿路症状评分（PLUTSS）进行评估，干预组在治疗后进行重新评估以衡量其反应。
在134名（59%）患者中检测到下尿路功能障碍。他们的平均PLUTSS为15.9±5.3，其中78%的患者生活质量（QOL）下降。经过5±2.7个月的行为治疗后，对105名（78%）LUTD患者进行了第二次评估。结果显示，69%的患者LUTD得到改善，26%的患者病情好转，治疗后平均PLUTSS为6.6±5.6。对照组有两名儿童患有LUTD。
UTI患者中经常出现下尿路功能障碍，但标准尿流疗法通常是成功的。我们研究中的大多数LUTD患者生活质量也受损。
