Kharchenko V P, Pan'shin G A, Khmelevskiĭ E V, Sotnikov V M, Zhdanov G P
Sov Med. 1989(1):15-7.
A method of combined organ-sparing treatment for first- or second-stage breast cancer has been developed. It includes large-fraction preoperative radiation (28.5 Gy in 5 daily fractions) and segmental mastectomy with axillary lymphadenectomy. The method has been used in 25 patients. Mean follow-up time is 23 months. No local or regional relapses have been recorded. Total relapse-free survival is 92%. The cosmetic and functional effect is satisfactory.
一种针对一期或二期乳腺癌的联合保器官治疗方法已被研发出来。它包括大分割术前放疗（5天内分5次给予28.5 Gy）以及保乳根治术加腋窝淋巴结清扫术。该方法已应用于25例患者。平均随访时间为23个月。未记录到局部或区域复发情况。总无复发生存率为92%。美容和功能效果令人满意。
