Mil'man M Sh, Abdusalamov A B
Ter Arkh. 1989;61(1):83-6.
A total of 133 patients aged 35 to 55 years with bronchial asthma (BA) were examined. Of these 85 patients showed an infection-dependent and 48 a steroid-dependent clinico-pathogenetic disease pattern. Physical performance was studied with regard to the character of occupation, the degree of respiratory function impairment and the effects of intal and orciprenaline sulfate on the reproducibility of asthma of effort (AE) and performance of that category of patients. The development of AE was found to lead to a further decrease of work fitness of BA patients irrespective of the clinico-pathogenetic disease pattern, the degree of external respiratory function impairment and the character of occupation, resulting in the limitation of physical work possibilities of BA patients. The data are also presented concerning the effects produced by intal and orciprenaline sulfate on AE reproducibility and work fitness of this group of patients and on the relationship between tracheobronchial hyper-reactivity and physical stimulus in the development of AE. Intal action was more pronounced as compared to orciprenaline sulfate. The data thus obtained can promote the improvement of the activity of the medical expert commission for evaluation of working capacity as well as of the standards of work recommendations in BA patients.
共对133例年龄在35至55岁之间的支气管哮喘(BA)患者进行了检查。其中85例患者表现为感染依赖性临床病理发病模式,48例为类固醇依赖性临床病理发病模式。从职业特点、呼吸功能损害程度以及异丙托溴铵和硫酸奥西那林对运动性哮喘(AE)再现性的影响和该类患者的运动能力方面对身体机能进行了研究。结果发现,无论临床病理发病模式、肺外呼吸功能损害程度和职业特点如何,AE的发生都会导致BA患者的工作适应性进一步下降,从而限制了BA患者的体力工作可能性。还给出了关于异丙托溴铵和硫酸奥西那林对该组患者AE再现性和工作适应性的影响以及气管支气管高反应性与AE发生时身体刺激之间关系的数据。与硫酸奥西那林相比,异丙托溴铵的作用更为显著。由此获得的数据有助于改进医学专家委员会评估工作能力的活动以及BA患者工作建议的标准。