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Social differences in lung cancer management and survival in South East England: a cohort study.英格兰东南部肺癌治疗与生存的社会差异：一项队列研究。
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J Epidemiol Community Health. 2008 Jan;62(1):75-80. doi: 10.1136/jech.2006.053207.
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癌症死亡率社会经济不平等的时间趋势：对英国男性进行的35年前瞻性研究结果

Time trends in socioeconomic inequalities in cancer mortality: results from a 35 year prospective study in British men.

作者信息

Ramsay Sheena E, Morris Richard W, Whincup Peter H, Papacosta Anna Olia, Lennon Lucy T, Wannamethee Sasiwarang Goya

机构信息

Department of Primary Care & Population Health, UCL, London, UK.

出版信息

BMC Cancer. 2014 Jun 30;14:474. doi: 10.1186/1471-2407-14-474.

DOI:10.1186/1471-2407-14-474
PMID:24975430
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4083875/
Abstract

BACKGROUND

Socioeconomic inequalities in cancer mortality in Britain have been shown to be present in the 1990s and early 2000s. Little is known about on-going patterns in such inequalities in cancer mortality. We examined time trends in socioeconomic inequalities in cancer mortality in Britain between 1978 and 2013.

METHODS

A socially representative cohort of 7489 British men with data on longest-held occupational social class, followed up for 35 years, in whom 1484 cancer deaths occurred.

RESULTS

The hazard ratio for cancer mortality for manual vs. non-manual social classes remained unchanged; among men aged 50-59 years it was 1.62 (95%CI 1.17-2.24) between 1980-1990 and 1.65 (95%CI 1.14-2.40) between 1990-2000. The absolute difference (non-manual minus manual) in probability of surviving death from cancer to 70 years remained at 3% over the follow-up. The consistency of risks over time was similar for both smoking-related and non-smoking related cancer mortality.

CONCLUSION

Socioeconomic inequalities in cancer mortality in Britain remain unchanged over the last 35 years and need to be urgently addressed.

摘要

背景

有证据表明，20世纪90年代和21世纪初英国癌症死亡率存在社会经济不平等现象。对于此类癌症死亡率不平等现象的持续模式，人们知之甚少。我们研究了1978年至2013年间英国癌症死亡率社会经济不平等的时间趋势。

方法

对7489名英国男性进行具有社会代表性的队列研究，这些男性拥有其长期从事职业的社会阶层数据，随访35年，其中有1484例癌症死亡病例。

结果

体力劳动者与非体力劳动者社会阶层的癌症死亡率风险比保持不变；在50 - 59岁男性中，1980 - 1990年间为1.62（95%置信区间1.17 - 2.24），1990 - 2000年间为1.65（95%置信区间1.14 - 2.40）。在随访期间，癌症死亡后存活至70岁的概率的绝对差异（非体力劳动者减去体力劳动者）保持在3%。吸烟相关和非吸烟相关癌症死亡率随时间的风险一致性相似。

结论

在过去35年中，英国癌症死亡率的社会经济不平等状况保持不变，亟待解决。