IgE antibodies to mountain cedar pollen predominantly recognize multiple conformational epitopes on Jun a 1.
作者信息
Goldblum Randall M, Ning Bo, Endsley Mark A, Estes D Mark, Judy Barbara M, van Bavel Julius, Midoro-Horiuti Terumi
机构信息
Department of Pediatrics, University of Texas Medical Branch, Galveston, Tex.
Allergy and Asthma Associates, Austin, Tex.
出版信息
J Allergy Clin Immunol. 2014 Oct;134(4):967-9.e7. doi: 10.1016/j.jaci.2014.05.009. Epub 2014 Jun 27.
Abstract
摘要
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本文引用的文献
1
Plant-expressed recombinant mountain cedar allergen Jun a 1 is allergenic and has limited pectate lyase activity.植物表达的重组山苍子过敏原 Jun a 1 具有变应原性，且具有有限的果胶裂解酶活性。
Int Arch Allergy Immunol. 2010;153(4):347-58. doi: 10.1159/000316345. Epub 2010 Jun 17.
2
Characteristic motifs for families of allergenic proteins.致敏蛋白家族的特征基序。
Mol Immunol. 2009 Feb;46(4):559-68. doi: 10.1016/j.molimm.2008.07.034. Epub 2008 Oct 31.
3
The property distance index PD predicts peptides that cross-react with IgE antibodies.特性距离指数PD可预测与IgE抗体发生交叉反应的肽段。
Mol Immunol. 2009 Feb;46(5):873-83. doi: 10.1016/j.molimm.2008.09.004. Epub 2008 Oct 23.
4
Major mountain cedar allergen, Jun a 1, contains conformational as well as linear IgE epitopes.主要的山地雪松过敏原Jun a 1含有构象性和线性IgE表位。
Mol Immunol. 2007 Apr;44(10):2781-5. doi: 10.1016/j.molimm.2005.12.001. Epub 2006 Jan 19.
5
Pollen allergens are restricted to few protein families and show distinct patterns of species distribution.花粉过敏原局限于少数蛋白质家族，并呈现出独特的物种分布模式。
J Allergy Clin Immunol. 2006 Jan;117(1):141-7. doi: 10.1016/j.jaci.2005.09.010. Epub 2005 Nov 28.
6
Dimerization of the major birch pollen allergen Bet v 1 is important for its in vivo IgE-cross-linking potential in mice.主要桦树花粉过敏原Bet v 1的二聚化对于其在小鼠体内的IgE交联潜力至关重要。
J Immunol. 2005 Nov 15;175(10):6645-50. doi: 10.4049/jimmunol.175.10.6645.
7
Crystal structure of Jun a 1, the major cedar pollen allergen from Juniperus ashei, reveals a parallel beta-helical core.来自阿什杜松的主要雪松花粉过敏原Jun a 1的晶体结构揭示了一个平行β-螺旋核心。
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8
Major linear IgE epitopes of mountain cedar pollen allergen Jun a 1 map to the pectate lyase catalytic site.山雪松花粉过敏原Jun a 1的主要线性IgE表位定位于果胶酸裂解酶催化位点。
Mol Immunol. 2003 Dec;40(8):555-62. doi: 10.1016/s0161-5890(03)00168-8.
9
Isolation and characterization of the mountain cedar (Juniperus ashei) pollen major allergen, Jun a 1.山地雪松（杜松）花粉主要变应原Jun a 1的分离与鉴定
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10
High-affinity oligonucleotide ligands to human IgE inhibit binding to Fc epsilon receptor I.与人IgE具有高亲和力的寡核苷酸配体可抑制其与Fcε受体I的结合。
J Immunol. 1996 Jul 1;157(1):221-30.
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