Güngör Tayfun, Akbay Serap, Aksüt Hayri, Yılmaz Bülent
Department of Obstetrics and Gynecology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey.
Department of Pathology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey.
J Turk Ger Gynecol Assoc. 2014 Jun 1;15(2):122-4. doi: 10.5152/jtgga.2014.53533. eCollection 2014.
Uterine leiomyosarcoma is an aggressive malignancy. Spread to the lung, thyroid, liver, brain, pancreas, heart, duodenum, breast, vagina, submandibular gland, and bone has been reported. We describe a case of metastatic uterine leiomyosarcoma to the rectus abdominalis muscle as the first case in the literature. A 39-year-old nulligravid woman presented with a history of pelvic pain. Physical examination discovered about a 6-cm mass in the suprapubic region. She had previously undergone a hysterectomy for uterine leiomyosarcoma. Operative findings had revealed a mass measuring 4×5×6 cm located in the rectus abdominalis muscle. Abnormal mitotic figures and necrosis were evident, and uterine leiomyosarcoma was diagnosed. Uterine leiomyosarcomas are malignancies of the smooth muscle arising from the myometrium. Skeletal muscle is an uncommon site of metastasis by hematogenous spread. In conclusion, we have described a case of skeletal muscle metastasis (first case of rectus abdominalis muscle metastasis) secondary to uterine leiomyosarcoma.
子宫平滑肌肉瘤是一种侵袭性恶性肿瘤。已有报道其可转移至肺、甲状腺、肝脏、脑、胰腺、心脏、十二指肠、乳腺、阴道、颌下腺和骨骼。我们报告一例子宫平滑肌肉瘤转移至腹直肌的病例，这是文献中首例此类病例。一名39岁未孕女性，有盆腔疼痛病史。体格检查发现耻骨上区域有一个约6厘米的肿块。她曾因子宫平滑肌肉瘤接受过子宫切除术。手术发现腹直肌中有一个4×5×6厘米的肿块。可见异常有丝分裂象和坏死，诊断为子宫平滑肌肉瘤。子宫平滑肌肉瘤是起源于子宫肌层的平滑肌恶性肿瘤。骨骼肌是血行转移不常见的部位。总之，我们描述了一例继发于子宫平滑肌肉瘤的骨骼肌转移病例（首例腹直肌转移病例）。
