马西利霍尔迪菌新种的非连续完成基因组序列及描述

Mishra Ajay Kumar, Lagier Jean-Christophe, Pfleiderer Anne, Nguyen Thi Thien, Caputo Aurelia, Raoult Didier, Fournier Pierre-Edouard

URMITE, CNRS 7278, IRD 198, Inserm U1095, Aix-Marseille Université, Faculté de Médecine, Marseille, France.

URMITE, CNRS 7278, IRD 198, Inserm U1095, Aix-Marseille Université, Faculté de Médecine, Marseille, France ; King Fahad Medical Research Center, King Abdul Aziz University, Jeddah, Saudi Arabia.

Stand Genomic Sci. 2013 Dec 15;9(2):395-409. doi: 10.4056/sigs.4628316. eCollection 2013 Dec 20.

Holdemania massiliensis strain AP2(T) sp. nov. is the type strain of H. massiliensis sp. nov., a new species within the genus Holdemania. This strain, whose genome is described here, was isolated from the fecal flora of a 21-year-old French Caucasian female suffering from severe restrictive anorexia nervosa. H. massiliensis is a Gram-positive, anaerobic bacillus. Here we describe the features of this organism, together with the complete genome sequence and annotation. The 3,795,625 bp-long genome (one chromosome but no plasmid) contains 3,461 protein-coding and 49 RNA genes, including 3 rRNA genes.

马赛霍尔迪菌AP2(T)菌株是马赛霍尔迪菌新物种的模式菌株，该新物种属于霍尔迪菌属。这里描述了其基因组的该菌株，是从一名患有严重限制性神经性厌食症的21岁法国白种女性的粪便菌群中分离得到的。马赛霍尔迪菌是一种革兰氏阳性厌氧杆菌。在此，我们描述该生物体的特征以及完整的基因组序列和注释。这个长度为3,795,625 bp的基因组（一条染色体但无质粒）包含3,461个蛋白质编码基因和49个RNA基因，其中包括3个rRNA基因。