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一名非酮症高血糖合并急性脑梗死患者在局灶性运动性癫痫持续状态后出现反复癫痫发作。

Recurrent seizures following focal motor status epilepticus in a patient with non-ketotic hyperglycemia and acute cerebral infarction.

作者信息

Lee Jung-Ju, Jung Jinwoong, Kang Kyusik, Park Jong-Moo, Shin Hyeeun, Kwon Ohyun, Kim Byung-Kun

机构信息

Department of Neurology, Eulji General Hospital, Eulji University College of Medicine, Seoul, Korea.

出版信息

J Epilepsy Res. 2014 Jun 30;4(1):28-30. doi: 10.14581/jer.14007. eCollection 2014 Jun.

Abstract

Focal motor status epilepticus (FMSE) is often associated non-ketotic hyperglycemia (NKH). There are no previous reports describing FMSE with NKH that was accompanied by an acute cerebral infarction and its long term follow-up result. We describe the case of a patient having focal motor status epilepticus (FMSE) associated with non-ketotic hyperglycemia (NKH) and acute cerebral infarction who later developed recurrent unprovoked seizures. A small acute infarct was observed in the left frontal subcortical area on diffusion-weighted images (DWI). FMSE was initially controlled with short term antiepileptic drugs and strict glucose control. Two years later, recurrent seizures occurred, and long-term antiepileptic drug treatment was administered. DWI should be considered for acute cerebral infarction in patients having FMSE associated with NKH, and careful follow-up should be conducted for such patients.

摘要

局灶性运动性癫痫持续状态(FMSE)常与非酮症高血糖(NKH)相关。此前尚无关于伴有急性脑梗死的FMSE合并NKH及其长期随访结果的报道。我们描述了一例患有与非酮症高血糖(NKH)和急性脑梗死相关的局灶性运动性癫痫持续状态(FMSE)的患者,该患者后来出现了反复发作的无诱因癫痫。在扩散加权成像(DWI)上,左侧额叶皮质下区域观察到一个小的急性梗死灶。FMSE最初通过短期抗癫痫药物和严格的血糖控制得以控制。两年后,癫痫复发,并给予了长期抗癫痫药物治疗。对于患有与NKH相关的FMSE的患者,应考虑进行DWI以排查急性脑梗死,并且应对此类患者进行密切随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901e/4066621/b7486c9598df/er-4-1-28-7f1.jpg

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