Infectious Diseases Research Unit, Department of Paediatrics, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain.
Clin Microbiol Infect. 2014 Dec;20(12):O1088-90. doi: 10.1111/1469-0691.12744. Epub 2014 Aug 13.
In order to determine if the novel influenza A(H1N1)pdm09 was associated with temporal trends of main serotypes causing invasive pneumococcal disease (IPD), we studied 384 episodes of IPD in <18-year-old patients from 2007 to 2012. The number of IPD episodes diagnosed during the 2009 pandemic period meant almost one-third of all the episodes diagnosed in the five included influenza periods (51/156). The number of IPD episodes diagnosed during the 2009 pandemic period meant almost one-third of all the episodes diagnosed in the five included influenza periods. Most of them occurred in <5-year-old children. Serotype 1 was the main serotype detected over the period, except for the 2009 pandemic, when it practically disappeared. Seasonality and viral infections could trigger temporal trends of serotypes causing IPD.
为了确定新型甲型 H1N1 流感是否与导致侵袭性肺炎球菌病（IPD）的主要血清型的时间趋势有关，我们研究了 2007 年至 2012 年间 384 例<18 岁患者的 IPD 发作。在 2009 年大流行期间诊断出的 IPD 发作数量意味着在包括流感在内的五个时期中诊断出的所有发作数量的近三分之一（51/156）。在 2009 年大流行期间诊断出的 IPD 发作数量意味着在包括流感在内的五个时期中诊断出的所有发作数量的近三分之一。其中大多数发生在<5 岁的儿童中。除了 2009 年大流行期间外，血清型 1 是整个期间检测到的主要血清型，当时它几乎消失了。季节性和病毒感染可能引发导致 IPD 的血清型的时间趋势。
