Balasubramaniam M, Sivapalan K, Thuvarathipan R
1Department of Physiology, Faculty of Medicine, University of Jaffna, Sri Lanka.
Ceylon Med J. 2014 Jun;59(2):49-53. doi: 10.4038/cmj.v59i2.7063.
To establish reference norms of lung function parameters for healthy Sri Lankan Tamil young adults.
Cross sectional study of Tamil students at the Faculty of Medicine, Jaffna.
Healthy non smoking students of Sri Lankan Tamil ethnic group were enrolled. Age, height, weight, BMI and spirometric measurements (Micro Quark) were recorded in 267 participants (137 females and 130 males).
Height was significantly correlated with (p<0.05) all the lung function parameters except FEV1%, PEFR and MEF75 in males. Prediction equations were derived by regression analysis based on the height as an independent variable. Predicted lung function values for a particular age and height were lower than values predicted for Pakistanis, Kelatanese Malaysians and eastern Indians. The values were comparable to south Indians in Madras. Our FVC values of males and VC of females were closer to Sri Lankan Sinhalese. FEV1 and FEF25-75 in males were slightly higher and FVC, FEV1 and FEF25-75 in females were slightly lower in Tamils. When mean values were compared, these parameters were significantly higher in Tamil males (p<0.001) and significantly lower in Tamil females (p<0.001).
These values will be useful in interpreting lung function parameters of the particular age group as there are no published norms for Sri Lankan Tamils. However, our study sample was confined to medical students of 20-28 years which may explain the differences with Sinhalese.
建立健康的斯里兰卡泰米尔族年轻成年人肺功能参数的参考标准。
对贾夫纳医学院的泰米尔族学生进行横断面研究。
招募健康的非吸烟斯里兰卡泰米尔族学生。记录了267名参与者(137名女性和130名男性)的年龄、身高、体重、体重指数和肺量计测量值(Micro Quark)。
男性的身高与除FEV1%、呼气峰值流速(PEFR)和最大呼气流量75%(MEF75)之外的所有肺功能参数均显著相关(p<0.05)。以身高作为自变量,通过回归分析得出预测方程。特定年龄和身高的预测肺功能值低于为巴基斯坦人、吉兰丹马来西亚人和东印度人预测的值。这些值与马德拉斯的南印度人相当。我们男性的用力肺活量(FVC)值和女性的肺活量(VC)值更接近斯里兰卡僧伽罗人。泰米尔族男性的第1秒用力呼气容积(FEV1)和25%-75%用力呼气流量(FEF25-75)略高,女性的FVC、FEV1和FEF25-75略低。当比较平均值时,这些参数在泰米尔族男性中显著更高(p<0.001),在泰米尔族女性中显著更低(p<0.001)。
由于没有针对斯里兰卡泰米尔族的已发表标准,这些值将有助于解释特定年龄组的肺功能参数。然而,我们的研究样本仅限于20至28岁的医学生,这可能解释了与僧伽罗人的差异。