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["膝关节周围骨肿瘤的手术治疗"]

[Surgery in «around the knee» bone tumors].

作者信息

Mattei Jean-Camille, Curvale Georges, Rochwerger Alexandre

机构信息

Hôpital de la Conception, Service d'orthopédie-traumatologie du Pr-Curvale, 147, boulevard Baille, 13005 Marseille, France.

出版信息

Bull Cancer. 2014 Jun;101(6):571-9. doi: 10.1684/bdc.2014.1983.

Abstract

Distal femur and proximal tibia are the main localization of primary malignant bone tumor. Osteosarcoma and Ewing sarcoma are the most frequent. New techniques in imaging, recent development in chemotherapy protocols and surgery sharpening led to major improvement in their management, which allowed to minimize amputation ratio. The complexity of their treatment and their rarity imply the involvement of multidisciplinary approach, in terms of both surgical and medical points of view. After resection, total knee arthroplasty has become the gold standard of reconstruction in such localizations. It uses press fit against healthy bone, thanks to long centromedullar stems, because of major soft tissues resection due to carcinologic surgery rules. The incision is usually antero-medial and the main difficulty is mostly linked to the care of vascular and nervous systems and the extensor apparatus. The conservation (or not) of the latter modifies the surgical technique. Articular invasion will impose to perform a one-piece-articular resection, which will complicate the conservation of the extensor apparatus. There are lots of different techniques and prosthesis. Arthrodesis indications are seldom because prosthesis reconstructions have made proof of their efficacy and their longevity. Functional and oncologic results of this excision and reconstructive surgery are now clearly established. However, this represents complex and risky interventions which will often lead to secondary surgical revision because of the young age of patients and their functional demands. This can only stress the necessity of addressing patients to specialized, network-organized sarcoma teams.

摘要

股骨远端和胫骨近端是原发性恶性骨肿瘤的主要发病部位。骨肉瘤和尤因肉瘤最为常见。成像新技术、化疗方案的最新进展以及手术技术的改进使得它们的治疗有了重大改善,截肢率得以降至最低。其治疗的复杂性和罕见性意味着从手术和医学角度来看都需要多学科方法。切除术后,全膝关节置换术已成为此类部位重建的金标准。由于肿瘤外科手术规则导致大量软组织切除,借助长的中心髓内柄,它采用压配固定于健康骨。切口通常为前内侧,主要困难大多与血管和神经系统以及伸肌装置的处理有关。伸肌装置的保留与否会改变手术技术。关节侵犯将需要进行整块关节切除,这会使伸肌装置的保留变得复杂。有许多不同的技术和假体。关节融合术的适应证很少,因为假体重建已证明其有效性和耐用性。这种切除和重建手术的功能和肿瘤学结果现已明确。然而,这是复杂且有风险的干预措施,由于患者年龄小及其功能需求,往往会导致二次手术翻修。这只能凸显将患者转至专业的、网络化组织的肉瘤治疗团队的必要性。

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