1Cardiovascular Physiology and Rehabilitation Laboratory, University of British Columbia, Vancouver, British Columbia, CANADA; 2Experimental Medicine Program, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, CANADA; and 3Physical Activity Promotion and Chronic Disease Prevention Unit, Vancouver, British Columbia, CANADA.
Med Sci Sports Exerc. 2015 Feb;47(2):280-8. doi: 10.1249/MSS.0000000000000423.
Indigenous populations currently experience greater rates of cardiovascular disease. Although ethnic differences in cardiovascular responses to exercise have previously been identified, these responses among indigenous populations are unknown.
This investigation aimed to evaluate the vascular responses to aerobic exercise of Canadian indigenous and European adults.
Twelve age- and sex-matched indigenous and European adults completed a cycle ergometer maximal aerobic power test and submaximal 30 min of 60% maximal aerobic capacity on two separate days. Blood pressure, pulse wave velocity, baroreceptor sensitivity, arterial compliance, vascular resistance, and intima-media thickness were directly measured before and after aerobic exercises.
Vascular responses to exercise were generally similar between indigenous and European adults including decreases in baroreceptor sensitivity and vascular resistance after maximal exercise. No changes in intima-media thickness, pulse wave velocity, and arterial compliance were observed after exercise in either group. However, after submaximal exercise, only European adults demonstrated reductions in baroreceptor sensitivity (spectral: 9.2 ± 4.3 to 11.5 ± 6.7 ms·mm Hg, P = 0.41, vs 15.8 ± 8.3 m·s to 8.9 ± 5.7 ms·mm Hg, P = 0.02; sequence: 14.6 ± 5.4 to 16.5 ± 11.0 ms·mm Hg, P = 0.48, vs 26.2 ± 10.5 m·s to 15.4 ± 9.4 ms·mm Hg, P = 0.02). Similarly, decreases in blood pressure after exercise were observed only among European adults.
Indigenous adults demonstrated vascular responses similar to those demonstrated by European adults, although blood pressure was only observed to decrease among European adults after maximal and submaximal exercise, and baroreceptor sensitivity, after submaximal exercise.
目前，土著人群的心血管疾病发病率更高。尽管先前已经确定了不同族裔人群在心血管运动反应方面存在差异，但土著人群的这些反应尚不清楚。
本研究旨在评估加拿大土著和欧洲成年人有氧运动的血管反应。
12 名年龄和性别匹配的土著和欧洲成年人在两天内分别完成了自行车测力计最大有氧能力测试和 60%最大有氧能力的 30 分钟亚最大运动。在有氧运动前后直接测量血压、脉搏波速度、压力感受性反射敏感性、动脉顺应性、血管阻力和内膜中层厚度。
运动对血管的反应在土著和欧洲成年人之间通常相似，包括最大运动后压力感受性反射敏感性和血管阻力下降。两组运动后内膜中层厚度、脉搏波速度和动脉顺应性均无变化。然而，在亚最大运动后，只有欧洲成年人的压力感受性反射敏感性降低（频谱：9.2 ± 4.3 至 11.5 ± 6.7 ms·mm Hg，P = 0.41，vs 15.8 ± 8.3 m·s 至 8.9 ± 5.7 ms·mm Hg，P = 0.02；序列：14.6 ± 5.4 至 16.5 ± 11.0 ms·mm Hg，P = 0.48，vs 26.2 ± 10.5 m·s 至 15.4 ± 9.4 ms·mm Hg，P = 0.02）。同样，只有欧洲成年人在运动后血压下降。
土著成年人的血管反应与欧洲成年人相似，尽管只有欧洲成年人在最大和亚最大运动后以及亚最大运动后的压力感受性反射敏感性观察到血压下降。
