Tiruveedhula Madhu, Reading Isabel C, Clarke Nicholas M P
*University Hospital Southampton Foundation Trust; Southampton General Hospital †NIHR Research Design Service South Central ‡University of Southampton and Child Health, University Hospital Southampton Foundation Trust, Southampton General Hospital, Southampton, UK.
J Pediatr Orthop. 2015 Mar;35(2):140-3. doi: 10.1097/BPO.0000000000000236.
Avascular necrosis (AVN) of the femoral head is an irreversible complication seen in the treatment of developmental dysplasia of hip (DDH) with the Pavlik harness. Its incidence is reported to be low after successful reduction of the hip but high if the hip is not concentrically relocated. We aim to investigate its incidence after failed Pavlik harness treatment.
We prospectively followed up a group of children who failed Pavlik harness treatment for DDH treated at our institution by the senior author between 1988 and 2001 and compared their rates of AVN with a group of children who presented late and hence were treated surgically. AVN was graded as described by Kalamchi and MacEwen and only grade 2 to 4 AVN was considered significant and included in the analysis.
Thirty-seven hips were included in the failed Pavlik group (group 1) and 86 hips in the no Pavlik group (group 2). Ten hips in group 1 developed AVN (27%), whereas only 7 hips in group 2 (8%) developed AVN; the odds of developing AVN after failed Pavlik treatment was 4.7 (95% confidence interval, 1.3-14.1) (P=0.009) with a relative risk of 3.32 (range, 1.37 to 8.05).
There was no statistically significant association observed with duration of splintage and severity of AVN (Spearman's correlation, -0.46; P=0.18). However, there was a positive correlation noted with age at presentation and severity of AVN. Therefore, we advise close monitoring of hips in the Pavlik harness and discontinue its use if the hips are not reduced within 3 weeks.
Level III.
股骨头缺血性坏死(AVN)是采用 Pavlik 吊带治疗发育性髋关节发育不良(DDH)时出现的一种不可逆并发症。据报道,髋关节成功复位后其发生率较低,但如果髋关节未实现同心复位则发生率较高。我们旨在研究 Pavlik 吊带治疗失败后的发生率。
我们对 1988 年至 2001 年期间由资深作者在我们机构接受 Pavlik 吊带治疗失败的一组 DDH 患儿进行了前瞻性随访,并将他们的 AVN 发生率与一组就诊较晚因此接受手术治疗的患儿进行比较。AVN 按照 Kalamchi 和 MacEwen 的描述进行分级,仅 2 至 4 级 AVN 被视为有意义并纳入分析。
Pavlik 治疗失败组(第 1 组)纳入 37 例髋关节,未使用 Pavlik 组(第 2 组)纳入 86 例髋关节。第 1 组中有 10 例髋关节发生 AVN(27%),而第 2 组中只有 7 例髋关节(8%)发生 AVN;Pavlik 治疗失败后发生 AVN 的几率为 4.7(95%置信区间,1.3 - 14.1)(P = 0.009),相对风险为 3.32(范围,1.37 至 8.05)。
未观察到固定时间与 AVN 严重程度之间存在统计学显著关联(Spearman 相关性,-0.46;P = 0.18)。然而,观察到就诊年龄与 AVN 严重程度呈正相关。因此,我们建议密切监测使用 Pavlik 吊带的髋关节,如果髋关节在 3 周内未复位则停止使用。
三级。