Babić Ivana Martinac, Marinović Branka
Acta Med Croatica. 2013 Dec;67(5):433-7.
Autoimmune diseases occur as a consequence of activity of one's own immune system against the body's own cells. Depending on target cells, autoimmune diseases are divided into organ-specific, i.e. those that affect only one organ or organ system, and systemic autoimmune diseases. In a large number of diseases belonging to this group, oral mucosa may be affected and the clinical picture can be very diverse. Oral lesions may occur in the earliest stages of autoimmune diseases, and some of them may be the first, or even the only manifestation. Given that many of these diseases can have serious life prediction, it is important to recognize changes in oral mucosa, diagnose them and start appropriate treatment on time. This paper deals with autoimmune diseases that often manifest on oral mucosa, such as autoimmune blistering diseases and lupus erythematosus.
自身免疫性疾病是由于自身免疫系统针对机体自身细胞的活动而发生的。根据靶细胞的不同，自身免疫性疾病分为器官特异性疾病，即仅影响一个器官或器官系统的疾病，以及系统性自身免疫性疾病。在属于这一组的大量疾病中，口腔黏膜可能会受到影响，临床表现可能非常多样。口腔病变可能出现在自身免疫性疾病的最早阶段，其中一些可能是首发表现，甚至是唯一表现。鉴于这些疾病中的许多可能具有严重的生命预后，识别口腔黏膜的变化、进行诊断并及时开始适当治疗非常重要。本文探讨了经常在口腔黏膜上表现出来的自身免疫性疾病，如自身免疫性水疱病和红斑狼疮。
