Krmek Dubravka Zupanić, Brajković Ivana, Bekić Dinko, Krnić Antun, Jurković Petar, Pavlović Tomislav
Acta Med Croatica. 2013 Dec;67(5):447-9.
In this article, we present a rare case of calcified deep vein thrombosis in a 42-year-old female patient with frequent relapses of pulmonary sarcoidosis since 1995, for which she was on maintenance therapy with corticosteroids and with consequential secondary diabetes. Recent femoral vein thrombosis was diagnosed with color Doppler in 2012. At the same time, calcified occlusive thrombus in vena cava inferior from the level of renal vein to the confluence of hepatic veins was diagnosed on abdominal multi-slice computed tomography (MSCT). Digital subtraction venography (DSV) revealed a well-developed collateral circulation through the paravertebral veins, azygos and hemiazygos vein. There were no risk factors for thrombosis other than sarcoidosis and diabetes. Deep vein thrombosis is rarely described with sarcoidosis, but according to literature reports, it usually appears as a recurrence and simultaneously at multiple locations. According to the current knowledge, we cannot say for sure whether it is a disease with an increased risk of deep vein thrombosis or there is a combination of multiple risk factors present simultaneously.
在本文中,我们报告了一例罕见的钙化性深静脉血栓形成病例,患者为一名42岁女性,自1995年以来肺结节病频繁复发,为此她接受了皮质类固醇维持治疗,并继发了糖尿病。2012年经彩色多普勒诊断为近期股静脉血栓形成。同时,腹部多层计算机断层扫描(MSCT)显示肾静脉水平至肝静脉汇合处的下腔静脉内有钙化闭塞性血栓。数字减影静脉造影(DSV)显示通过椎旁静脉、奇静脉和半奇静脉形成了良好的侧支循环。除结节病和糖尿病外,无其他血栓形成危险因素。结节病很少伴有深静脉血栓形成,但根据文献报道,其通常表现为复发且同时发生于多个部位。根据目前的认识,我们无法确定它是否是一种深静脉血栓形成风险增加的疾病,还是同时存在多种危险因素的组合。