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两个亚洲国家诺普兰使用者的出血模式及可接受性

Bleeding patterns and acceptability among Norplant users in two Asian countries.

作者信息

Balogh S A, Klavon S L, Basnayake S, Puertollano N, Ramos R M, Grubb G S

机构信息

Family Health International, Research Triangle Park, NC 27709.

出版信息

Contraception. 1989 May;39(5):541-53. doi: 10.1016/0010-7824(89)90109-1.

Abstract

Changes in menstrual bleeding patterns are the most frequent reason for discontinuing NORPLANT during the first year of use. Although NORPLANT is used by more women in Asia than in any other region, the changes that occur among these women are not well documented. In pre-introductory clinical trials of NORPLANT in the Philippines and Sri Lanka, 175 women were enrolled with greater than 95% continuing the method after one year. Daily menstrual bleeding calendars were kept by 94% of subjects for nine months and by 66% for one year. In contrast to findings in previous studies which showed that approximately 60% of NORPLANT users had bleeding disruptions in the first year of use, almost all of these women experienced bleeding disruptions. In a one-year study of menstrual pattern changes, increased bleeding was found to occur with the same frequency as reduced bleeding. However, the changes experienced by the Asian women tended to be decreases, rather than increases, in menstrual bleeding.

摘要

月经出血模式的改变是在使用诺普兰(皮下埋植避孕剂)的第一年中停用该药的最常见原因。尽管在亚洲使用诺普兰的女性比其他任何地区都多,但这些女性中出现的变化并未得到充分记录。在菲律宾和斯里兰卡进行的诺普兰引入前临床试验中,招募了175名女性,一年后超过95%的人继续使用该方法。94%的受试者记录了九个月的每日月经出血情况,66%的受试者记录了一年。与之前研究结果显示约60%的诺普兰使用者在使用第一年出现出血紊乱不同,几乎所有这些女性都经历了出血紊乱。在一项为期一年的月经模式变化研究中,发现出血增加和出血减少的频率相同。然而,亚洲女性经历的变化往往是月经出血量减少,而非增加。

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