Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, 2048 Vet Med, Ames, IA 50011, USA.
Vet Clin North Am Food Anim Pract. 2014 Jul;30(2):359-81, vi. doi: 10.1016/j.cvfa.2014.04.003.
Hypocalcemia is a clinical disorder that can be life threatening to the cow (milk fever) and predisposes the animal to various other metabolic and infectious disorders. Calcium homeostasis is mediated primarily by parathyroid hormone, which stimulates bone calcium resorption and renal calcium reabsorption. Parathyroid hormone stimulates the production of 1,25-dihydroxyvitamin D to enhance diet calcium absorption. High dietary cation-anion difference interferes with tissue sensitivity to parathyroid hormone. Hypomagnesemia reduces tissue response to parathyroid hormone.
低钙血症是一种临床疾病,可对奶牛(乳热)造成生命威胁,并使动物易患各种其他代谢和传染性疾病。钙稳态主要由甲状旁腺激素调节,甲状旁腺激素刺激骨钙吸收和肾脏钙重吸收。甲状旁腺激素刺激 1,25-二羟维生素 D 的产生,以增强饮食钙的吸收。高膳食阳离子-阴离子差会干扰组织对甲状旁腺激素的敏感性。低镁血症会降低组织对甲状旁腺激素的反应。