Levesque E, Suet G, Merle J C, Compagnon P, Amathieu R, Feray C, Botterel F, Foulet F, Azoulay D, Dhonneur G
Réanimation digestive, Service d'Anesthésie et des Réanimations Chirurgicales, GH Henri Mondor, Créteil, France.
Transpl Infect Dis. 2014 Oct;16(5):827-9. doi: 10.1111/tid.12260. Epub 2014 Jul 1.
Infections remain a major cause of morbidity and mortality after liver transplantation. One possible cause of infection is preservation fluid contamination. Donor-derived pathogens, such as Candida albicans, have occasionally produced life-threatening complications in organ recipients, already described in renal transplantation. In the present case, we report the loss of a liver graft secondary to vascular complications because of C. albicans found in the preservation fluid. Our case report raises the question of implementing procedures, similar to those in renal transplantation, including early antifungal treatment and repeated radiological monitoring for the prevention and detection of vascular complications.
感染仍然是肝移植后发病和死亡的主要原因。感染的一个可能原因是保存液污染。供体来源的病原体,如白色念珠菌,偶尔会在器官接受者中引发危及生命的并发症,肾移植中已有相关描述。在本病例中,我们报告了因保存液中发现白色念珠菌继发血管并发症导致肝移植失败的情况。我们的病例报告提出了一个问题,即是否应实施类似于肾移植的程序,包括早期抗真菌治疗和反复进行放射学监测,以预防和检测血管并发症。