El-Bandar Nasrin, Kroy Daniela C, Fuller Tom Florian, Kramer Jürgen, Liefeldt Lutz, Budde Klemens, Blobel Conrad, Miller Kurt, Friedersdorff Frank
Department of Urology, Charité University Hospital Berlin, Berlin, Germany.
Department of Medicine III, RWTH University Hospital Aachen, Aachen, Germany.
Am J Case Rep. 2017 Jul 11;18:777-781. doi: 10.12659/ajcr.904119.
BACKGROUND Graft-site candidiasis rarely develops in solid organ transplant recipients; however, severe life-threatening complications can occur. We report the course of 3 solid organ transplant recipients developing graft-site candidiasis. CASE REPORT All grafts, consisting of 2 kidneys and 1 liver, were procured from a single donor. Patient data were collected from our database. Candida albicans was isolated from a swab taken during multiple-organ recovery. Complications associated with candidiasis occurred in all 3 recipients with preservation of the liver transplant. Both renal transplant recipients had vascular complications, eventually resulting in graft nephrectomy and subsequent return to dialysis. The patients recovered completely without residual effects of their prior fungal infection. CONCLUSIONS Fungal infections in solid organ transplant recipients are rare. Since the sequelae of these infections are serious and usually pertain to more than 1 recipient at a time, antifungal prophylaxis may be warranted in select donors.
实体器官移植受者很少发生移植部位念珠菌病；然而，可能会出现严重的危及生命的并发症。我们报告了3例实体器官移植受者发生移植部位念珠菌病的病程。病例报告：所有移植物，包括2个肾脏和1个肝脏，均来自单一供体。患者数据从我们的数据库中收集。白色念珠菌是在多器官恢复过程中从拭子中分离出来的。所有3例接受肝脏移植的受者均发生了与念珠菌病相关的并发症。两名肾移植受者均出现血管并发症，最终导致移植肾切除术并随后恢复透析。患者完全康复，先前真菌感染没有残留影响。结论：实体器官移植受者的真菌感染很少见。由于这些感染的后遗症很严重，而且通常一次涉及不止1名受者，因此在某些供体中可能有必要进行抗真菌预防。
