von Neuhoff Nils, Pich Andreas
Institute of Cell and Molecular Pathology, OE 5120, Hannover Medical School, Germany.
Department of Toxicology, Hannover Medical School, Germany.
Drug Discov Today Technol. 2005 Winter;2(4):361-7. doi: 10.1016/j.ddtec.2005.11.011.
The use of modern mass spectroscopy methods has made proteomics a promising new tool for the clinical diagnosis of cancer and other diseases. Because body fluids like plasma, serum or liquor can be analyzed, proteomics should be easily integrated into large clinical trials. However, before proteomics can be implemented, rigorous quality control is urgently needed. One of the major topics of proteomics is the search for specific biomarkers which can be used for the qualitative and quantitative judgment of a disease.:
现代质谱方法的应用使蛋白质组学成为一种用于癌症和其他疾病临床诊断的有前景的新工具。由于可以分析血浆、血清或脑脊液等体液，蛋白质组学应易于整合到大型临床试验中。然而，在实施蛋白质组学之前，迫切需要严格的质量控制。蛋白质组学的主要课题之一是寻找可用于疾病定性和定量判断的特定生物标志物。
