注意力缺陷多动障碍的INCLEN诊断工具（INDT-ADHD）：开发与验证

INCLEN diagnostic tool for attention deficit hyperactivity disorder (INDT-ADHD): development and validation.

作者信息

Mukherjee Sharmila, Aneja Satinder, Russell Paul S S, Gulati Sheffali, Deshmukh Vaishali, Sagar Rajesh, Silberberg Donald, Bhutani Vinod K, Pinto Jennifer M, Durkin Maureen, Pandey Ravindra M, Nair M K C, Arora Narendra K

机构信息

The INCLEN Trust International, New Delhi, India. Correspondence to: Dr Narendra K Arora, Executive Director, The INCLEN Trust International, F1/5, Okhla Industrial Area, Phase-1, New Delhi, India.

出版信息

Indian Pediatr. 2014 Jun;51(6):457-62. doi: 10.1007/s13312-014-0436-6.

DOI:10.1007/s13312-014-0436-6

PMID:24986281

Abstract

OBJECTIVE

To develop and validate INCLEN Diagnostic Tool for Attention Deficit Hyperactivity Disorder (INDT-ADHD).

DESIGN

Diagnostic test evaluation by cross sectional design.

SETTING

Tertiary care pediatric centers.

PARTICIPANTS

156 children aged 65-117 months.

METHODS

After randomization, INDT-ADHD and Connors 3 Parent Rating Scale (C3PS) were administered, followed by an expert evaluation by DSM-IV-TR diagnostic criteria.

MAIN OUTCOME MEASURES

Psychometric evaluation of diagnostic accuracy, validity (construct, criterion and convergent) and internal consistency.

RESULTS

INDT-ADHD had 18 items that quantified symptoms and impairment. Attention deficit hyperactivity disorder was identified in 57, 87 and 116 children by expert evaluation, INDT-ADHD and C3PS, respectively. Psychometric parameters of INDT-ADHD for differentiating attention deficit hyperactivity disorder and normal children were: sensitivity 87.7%, specificity 97.2%, positive predictive value 98.0% and negative predictive value 83.3%, whereas for differentiating from other neuro-developmental disorders were 87.7%, 42.9%, 58.1% and 79.4%, respectively. Internal consistency was 0.91. INDT-ADHD has a 4-factor structure explaining 60.4% of the variance. Convergent validity with Conner's Parents Rating Scale was moderate (r =0.73, P= 0.001).

CONCLUSIONS

INDT-ADHD is suitable for diagnosing attention deficit hyperactivity disorder in Indian children between the ages of 6 to 9 years.

摘要

目的

开发并验证注意力缺陷多动障碍印度国家儿童健康与发展研究中心诊断工具（INDT - ADHD）。

设计

采用横断面设计进行诊断测试评估。

地点

三级护理儿科中心。

参与者

156名年龄在65至117个月的儿童。

方法

随机分组后，使用INDT - ADHD和康纳斯父母评定量表第三版（C3PS）进行评估，随后依据《精神疾病诊断与统计手册》第四版修订版（DSM - IV - TR）诊断标准进行专家评估。

主要观察指标

对诊断准确性、效度（结构效度、效标效度和会聚效度）及内部一致性进行心理测量学评估。

结果

INDT - ADHD有18个量化症状和损害的条目。通过专家评估、INDT - ADHD和C3PS分别诊断出患有注意力缺陷多动障碍的儿童数量为57、87和116名。INDT - ADHD区分注意力缺陷多动障碍儿童与正常儿童的心理测量学参数为：敏感度87.7%，特异度97.2%，阳性预测值98.0%，阴性预测值83.3%；而区分注意力缺陷多动障碍儿童与其他神经发育障碍儿童的相应参数分别为87.7%、42.9%、58.1%和79.4%。内部一致性为0.91。INDT - ADHD具有一个四因素结构，可解释60.4%的方差变异。与康纳斯父母评定量表的会聚效度为中等程度（r = 0.73，P = 0.001）。