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基于 DSM-5 的 AIIMS 改良 INDT ADHD 工具的制定与验证:用于 ADHD 诊断的诊断测试评估研究。

The Development and Validation of DSM 5-Based AIIMS-Modified INDT ADHD Tool for Diagnosis of ADHD: A Diagnostic Test Evaluation Study.

机构信息

Child Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, Delhi, India.

The INCLEN Trust International, 2nd Floor, F-1/5, Okhla Industrial Area, Phase-I, New Delhi, India.

出版信息

Neurol India. 2020 Mar-Apr;68(2):352-357. doi: 10.4103/0028-3886.280638.

DOI:10.4103/0028-3886.280638
PMID:32189699
Abstract

BACKGROUND

The current study was planned at a tertiary centre in northern India to develop and validate a Diagnostic and Statistical Manual-5 (DSM-5)-based diagnostic tool and design a severity score for attention deficit hyperactivity disorder (ADHD) in children aged 6-18 years. An existing DSM-IV-based tool, INDT (International Clinical Epidemiology Network [INCLEN] diagnostic tool) for ADHD has been modified and named All India Institute of Medical Sciences (AIIMS)-modified INDT ADHD tool.

METHOD

The first phase was development of the tool and the second phase was validation of the same against the gold standard of diagnosis by the DSM-5. A severity score was developed for ADHD in concordance with the Conners rating scale.

RESULTS

The tool was validated in 66 children with a sensitivity and specificity of 100 per cent and 90 per cent, respectively. A cut-off score of 12 was decided for labelling severity of ADHD, which corresponded to 63 in the Conners rating scale.

CONCLUSION

This diagnostic tool for ADHD based on DSM-5 has acceptable psychometric properties. The severity score will be useful for prognostication, monitoring treatment response, and designing intervention trials.

摘要

背景

本研究在印度北部的一家三级中心进行,旨在开发和验证基于《精神障碍诊断与统计手册第五版》(DSM-5)的诊断工具,并为 6-18 岁儿童设计注意力缺陷多动障碍(ADHD)严重程度评分。现有的基于 DSM-IV 的 ADHD 诊断工具 INDT(国际临床流行病学网络 [INCLEN] 诊断工具)已被修改,并命名为全印度医学科学研究所(AIIMS)-改良 INDT ADHD 工具。

方法

第一阶段是开发工具,第二阶段是根据 DSM-5 的金标准对其进行验证。根据 Conners 评定量表,为 ADHD 制定了严重程度评分。

结果

该工具在 66 名儿童中进行了验证,其敏感性和特异性分别为 100%和 90%。将 ADHD 的严重程度标记为 12 分,这与 Conners 评定量表中的 63 分相对应。

结论

基于 DSM-5 的 ADHD 诊断工具具有可接受的心理测量特性。严重程度评分将有助于预测、监测治疗反应和设计干预试验。

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