Bruni Antonella, Gianicolo Emilio Antonio Luca, Vigotti Maria Angela, Faustini Annunziata
Istituto di fisiologia clinica, Consiglio nazionale delle ricerche, Lecce
Epidemiol Prev. 2014 Mar-Apr;38(2):108-15.
to estimate the prevalence of chronic obstructive pulmonary disease (COPD) in Brindisi Province (Southern Italy) during the period 2005-2009.
longitudinal approach using electronic health data.
prevalence of COPD cases where defined as: 35+ year-old residents in Brindisi Province discharged from hospital with a diagnosis of COPD, recorded in any of the diagnostic fields, during the period 2005-2009; residents discharged in the previous 4 years and still alive at the beginning of the year considered; residents who died of COPD without previous hospital admissions for the same disease. Diagnoses codes selected from discharge data and cause of mortality archive were 490-492, 494 and 496, of the International Classification of Diseases - IX Revision - Clinical Modification (ICD-9-CM).
crude prevalence and age standardized prevalence (per 100 residents), with confidence intervals (95%CI), by gender.
COPD prevalence rates did not change in Brindisi Province over the period of study and the rate was around 6.6%. Prevalence was higher in males and increased with age both among males and females. The rates were higher among the females resident in Brindisi town than those observed among females resident in the rest of the municipalities of the Province considered. Among males, prevalence rates were similar between males living in the selected areas.
this study is the first to present COPD prevalence rates estimated for the Brindisi Province based on electronic health data. The results showed a higher COPD prevalence in Brindisi then in other Italian cities and spatial and temporal differences by gender among Brindisi and the rest of the municipalities considered. Results require additional investigations. In particular, the use of additional health data sources not considered in the present study might help in better explaining the differences observed.
评估2005 - 2009年期间意大利南部布林迪西省慢性阻塞性肺疾病（COPD）的患病率。
采用电子健康数据的纵向研究方法。
COPD病例的患病率定义为：2005 - 2009年期间，布林迪西省35岁及以上因COPD诊断出院的居民，记录于任何诊断字段；前4年出院且在评估年初仍存活的居民；因COPD死亡但此前未因该疾病住院的居民。从出院数据和死亡原因档案中选取的诊断编码为国际疾病分类第九版临床修订本（ICD - 9 - CM）中的490 - 492、494和496。
按性别划分的粗患病率和年龄标准化患病率（每100名居民），并给出置信区间（95%CI）。
在研究期间，布林迪西省的COPD患病率没有变化，患病率约为6.6%。男性患病率更高，且男性和女性的患病率均随年龄增长而增加。布林迪西镇女性居民的患病率高于该省其他市镇女性居民的患病率。在男性中，所选地区男性的患病率相似。
本研究首次基于电子健康数据呈现了布林迪西省的COPD患病率估计值。结果显示，布林迪西省的COPD患病率高于意大利其他城市，且在布林迪西与其他市镇之间存在性别上的时空差异。结果需要进一步调查。特别是，使用本研究未考虑的其他健康数据源可能有助于更好地解释观察到的差异。
