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腹痛症状的研究——一项系统评价与荟萃分析

Studies of the symptom abdominal pain--a systematic review and meta-analysis.

作者信息

Viniol Annika, Keunecke Christian, Biroga Tobias, Stadje Rebekka, Dornieden Katharina, Bösner Stefan, Donner-Banzhoff Norbert, Haasenritter Jörg, Becker Annette

机构信息

Department of General Practice/Family Medicine, University of Marburg, Marburg, Germany.

出版信息

Fam Pract. 2014 Oct;31(5):517-29. doi: 10.1093/fampra/cmu036. Epub 2014 Jul 1.

Abstract

BACKGROUND

Diagnostic reasoning in primary care patients with abdominal pain is a complex challenge for GPs. To ensure evidence-based decision making for this symptom, GPs need setting-specific knowledge about the prevalence, potential risks for diseases and chance of recovery or risk of undesirable courses of disease.

AIM

We conducted a systematic review of symptom-evaluating studies on prevalence, aetiology or prognosis of abdominal pain.

METHODS

We included all studies evaluating the symptom 'abdominal pain' as a reason for consultation in primary care. We included all types of study designs except for qualitative studies. Studies focussed solely on children or settings other than primary care were also excluded.

RESULTS

We identified 14 studies. Mean consultation prevalence is 2.8% for abdominal pain. In about one-third of patients the underlying cause of abdominal pain cannot be specified. The most common aetiologies are gastroenteritis (7.2-18.7%), irritable bowel disease (2.6-13.2%), urological cause (5.3%) and gastritis (5.2%). About 1 in 10 abdominal pain patients suffers from an acute disease like appendicitis (1.9%), diverticulitis (3.0%), biliary/pancreatic (4.0%) or neoplastic (1.0%) diseases needing immediate therapy.

CONCLUSION

There is a high prevalence of patients consulting GPs for abdominal pain. The review identified a comparably high rate of acute underlying diseases in need of further investigation or therapy. At the same time, the underlying cause of the complaints often remains unexplained. Further symptom-evaluating studies are necessary, ideally using standardized methodology in order to gain sufficient evidence for developing much-needed guidelines and decision support tools.

摘要

背景

对于全科医生而言,对腹痛的初级护理患者进行诊断推理是一项复杂的挑战。为了确保针对该症状做出基于证据的决策,全科医生需要特定环境下有关疾病患病率、潜在风险以及康复几率或不良病程风险的知识。

目的

我们对有关腹痛患病率、病因或预后的症状评估研究进行了系统综述。

方法

我们纳入了所有将“腹痛”症状作为初级护理中就诊原因进行评估的研究。除定性研究外,我们纳入了所有类型的研究设计。仅关注儿童或初级护理以外环境的研究也被排除。

结果

我们确定了14项研究。腹痛的平均就诊患病率为2.8%。约三分之一的患者腹痛的潜在病因无法明确。最常见的病因是肠胃炎(7.2 - 18.7%)、肠易激综合征(2.6 - 13.2%)、泌尿系统病因(5.3%)和胃炎(5.2%)。每10名腹痛患者中约有1人患有需要立即治疗的急性疾病,如阑尾炎(1.9%)、憩室炎(3.0%)、胆道/胰腺疾病(4.0%)或肿瘤疾病(1.0%)。

结论

因腹痛就诊于全科医生的患者患病率较高。该综述发现需要进一步调查或治疗的急性潜在疾病发生率相对较高。同时,主诉的潜在病因往往仍无法解释。有必要开展进一步的症状评估研究,理想情况下采用标准化方法,以便获得足够的证据来制定急需的指南和决策支持工具。

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