Al-Baghli N A, Al-Turki K A, Al-Ghamdi A J, Prasad K, Taha A Z, Al-Almaie S M
Directorate of Health Affairs, Ministry of Health, Dammam, Saudi Arabia.
Ministry of Health, Riyadh, Saudi Arabia.
East Mediterr Health J. 2012 Dec 4;16(12):1237-44. doi: 10.26719/2010.16.12.1237.
This study compared 2 screening tests for detecting undiagnosed diabetes mellitus when applied in a mass-screening campaign in the Eastern province of Saudi Arabia in 2004-05. Of 15 082 individuals screened, 65.8% were positive by the American Diabetes Association risk-score questionnaire and 71.3% by determination of capillary blood glucose (CBG) using a portable glucometer. Type 2 diabetes mellitus was confirmed in 20.3% of participants and pre-diabetes in 33.9% using fasting venous blood testing. The risk-score questionnaire did not perform well versus fasting and random CBG. Optimal cut-offs for fasting and random CBG were 120 mg/dL and 160 mg/dL respectively. Fasting CBG had higher sensitivity, specificity and discriminating ability than random CBG for detection of diabetes and pre-diabetes in this population.
本研究比较了2004 - 2005年在沙特阿拉伯东部省份开展的大规模筛查活动中，用于检测未确诊糖尿病的两种筛查测试。在接受筛查的15082人中，65.8%的人通过美国糖尿病协会风险评分问卷呈阳性，71.3%的人通过使用便携式血糖仪测定毛细血管血糖（CBG）呈阳性。通过空腹静脉血检测，20.3%的参与者被确诊为2型糖尿病，33.9%为糖尿病前期。与空腹和随机CBG相比，风险评分问卷的表现不佳。空腹和随机CBG的最佳临界值分别为120mg/dL和160mg/dL。在该人群中，空腹CBG在检测糖尿病和糖尿病前期方面比随机CBG具有更高的敏感性、特异性和鉴别能力。
