宽松挂线疗法在肛瘘治疗中的作用:一项针对200例患者的多中心研究。

The role of loose seton in the management of anal fistula: a multicenter study of 200 patients.

作者信息

Kelly M E, Heneghan H M, McDermott F D, Nason G J, Freeman C, Martin S T, Winter D C

机构信息

Department of Surgery, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland,

出版信息

Tech Coloproctol. 2014 Oct;18(10):915-9. doi: 10.1007/s10151-014-1186-0. Epub 2014 Jul 3.

Abstract

BACKGROUND

Perianal abscesses and fistulae-in-ano are a common anorectal complaint causing significant distress to patients, and present a considerable treatment challenge. Principal of treatment is achieving closure of the fistula while maintaining continence. There are numerous treatment approaches with large debate about which method is "ideal." Our aim was to assess the tolerance and efficacy of loose seton placement in the treatment for fistula-in-ano.

METHODS

We performed a retrospective multicenter review of the management of anal fistulae with loose seton placement over a three-year period. All patients underwent a standardized procedure, and were rescheduled for an elective change of seton until fistula resolution. Patients' demographics, medical history, comorbidities, overall number and time interval between seton placements, tolerance, and morbidity of the procedure were recorded.

RESULTS

A total of 200 consecutive patients had loose seton placement. 69.5 % (n = 139) were males, and mean age was 42.6 years. The median number of setons required for each patient was 3 (range 1-8; mean 2.84). The mean interval between changes was 3.08 months (range 2-4 months). All patients had successful clearance of fistula. The procedure was well tolerated in 96 % of patients (n = 187). Only 1 % (n = 2) could not tolerate the presence of seton due to significant discomfort. Fistula recurrence rate was 6 % (n = 12).

CONCLUSIONS

Recently, newer treatment modalities have been reported with enthusiasm. However, there remains a lack of strong statistical evidence of efficacy to support their use. Overall, loose seton placement remains a well-tolerated, pragmatic low-cost solution to this common and difficult condition as evident by our study.

摘要

背景

肛周脓肿和肛瘘是常见的肛肠疾病,给患者带来极大痛苦,也带来了相当大的治疗挑战。治疗的主要原则是在保持控便能力的同时实现肛瘘闭合。治疗方法众多,关于哪种方法是“理想方法”存在大量争议。我们的目的是评估宽松挂线疗法治疗肛瘘的耐受性和疗效。

方法

我们对三年期间采用宽松挂线疗法治疗肛瘘的情况进行了回顾性多中心研究。所有患者均接受标准化手术,并安排择期更换挂线,直至肛瘘愈合。记录患者的人口统计学资料、病史、合并症、挂线的总数和间隔时间、耐受性以及手术的发病率。

结果

共有200例连续患者接受了宽松挂线疗法。69.5%(n = 139)为男性,平均年龄为42.6岁。每位患者所需挂线的中位数为3(范围1 - 8;平均2.84)。更换挂线的平均间隔时间为3.08个月(范围2 - 4个月)。所有患者的肛瘘均成功治愈。96%(n = 187)的患者对该手术耐受性良好。只有1%(n = 2)的患者因严重不适无法耐受挂线。肛瘘复发率为6%(n = 12)。

结论

最近,有新的治疗方式被热情报道。然而,仍缺乏有力的统计学证据支持其有效性。总体而言,如我们的研究所示,宽松挂线疗法对于这种常见且棘手的病症仍是一种耐受性良好、实用且低成本的解决方案。

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