Dudchenko M A, Skrypnikova T P, Dudchenko M A
Stomatologiia (Mosk). 2014;93(3):4-7.
It is currently proved ulcerous stomatitis and duodenal ulcer to have common pathogenetic infectious link (the most studied agent being Helicobacter pylori) by concominant decrease of local and general immunity with hyperoxidation events. Eighty patients (44 female and 36 male aged 15-60) with chronic aphthous stomatitis (AS) combined with duodenal ulcer were included in the study and divided in two equal groups according to treatment received (control group of 40 patients was treated according to conventional scheme, while in 40 patients a new formulation Vipromak was added to treatment protocol). The symptoms of AS tend to resolve faster in vipromak group thus proving its efficiency in treatment of AS and duodenal ulcer.
目前已证实，溃疡性口炎和十二指肠溃疡通过局部和全身免疫力的同时下降以及过氧化事件存在共同的致病感染环节（研究最多的病原体是幽门螺杆菌）。本研究纳入了80例患有慢性阿弗他口炎（AS）合并十二指肠溃疡的患者（44例女性，36例男性，年龄在15至60岁之间），并根据所接受的治疗将其分为两组（对照组40例患者按照传统方案治疗，而另外40例患者在治疗方案中添加了新制剂Vipromak）。Vipromak组中AS的症状往往更快缓解，从而证明了其在治疗AS和十二指肠溃疡方面的有效性。
