脂质肺炎作为洛伦佐油疗法在一名肾上腺脑白质营养不良患者中的并发症。

Lipoid pneumonia as a complication of Lorenzo's oil therapy in a patient with adrenoleukodystrophy.

作者信息

Majori Maria, Scarascia Alessandro, Anghinolfi Miriam, Pisi Roberta, Gnetti Letizia, Casalini Angelo Gianni

机构信息

*Pulmonology and Thoracic Endoscopy Unit †Respiratory Disease Unit ‡Pathologic Anatomy Unit, University Hospital of Parma, Parma, Italy.

出版信息

J Bronchology Interv Pulmonol. 2014 Jul;21(3):271-3. doi: 10.1097/LBR.0000000000000084.

DOI:10.1097/LBR.0000000000000084

PMID:24992138

Abstract

Lipoid pneumonia (LP) is a rare exogenous condition caused by inhalation or aspiration of lipid material into the lungs. It is often associated with the therapeutic use of different types of oil, and the diagnosis is based on the demonstration of lipid-laden macrophages in bronchoalveolar lavage fluid. We reported the case of a 39-year-old male with X-linked adrenoleukodystrophy who developed LP secondary to the use of Lorenzo's oil. To our knowledge, the association between the use of Lorenzo's oil and LP has never been reported in literature.

摘要

类脂性肺炎（LP）是一种罕见的外源性疾病，由脂质物质吸入或误吸进入肺部所致。它常与不同类型油类的治疗应用相关，诊断基于支气管肺泡灌洗 fluid 中发现含脂巨噬细胞。我们报告了一例39岁患有X连锁肾上腺脑白质营养不良的男性患者，其因使用洛伦佐油而继发LP。据我们所知，使用洛伦佐油与LP之间的关联在文献中从未有过报道。（注：原文中“bronchoalveolar lavage fluid”翻译为“支气管肺泡灌洗 fluid”，此处“fluid”可能是“fluid”拼写错误，正确应为“fluid”即“液体”，完整应是“支气管肺泡灌洗液” ）