Ihnát Peter, Martínek Lubomír, Mitták Marcel, Vávra Petr, Ihnát Rudinská Lucia, Zonča Pavel
Department of Surgery, University Hospital Ostrava, Ostrava, Czech Republic.
Dig Surg. 2014;31(3):161-8. doi: 10.1159/000363415. Epub 2014 Jul 2.
The aim of the study was to evaluate quality of life (QOL) outcomes after colorectal surgery for cancer from a 6-month perspective at a single institution.
Cohort study to prospectively assess postoperative QOL in patients who underwent elective colorectal resection at the University Hospital Ostrava. QOL was assessed using the validated Short Form 36 (SF-36v2™) questionnaire at fixed time points.
A total of 148 patients were enrolled in the study (83 and 65 patients underwent laparoscopic and open colorectal resection, respectively). Operative time was significantly longer (161 vs. 133 min; p = 0.0073) and length of hospital stay was significantly shorter (10.7 vs. 13.1 days; p = 0.0451) in the laparoscopic group. Overall 30-day morbidity rates were lower in the laparoscopic group, but the difference was not significant (27.7 vs. 33.8%; p = 0.2116). QOL scores were comparable in both study groups before surgery (p ≥ 0.05). QOL was statistically significantly lower 2 days and 1 week after open colorectal surgery compared with laparoscopic surgery. One month and 6 months after surgery, there were no statistically significant differences between groups.
The present study suggests a higher postoperative QOL during the first month after laparoscopic colorectal resection could be one of the benefits of laparoscopy.
本研究旨在从单一机构的6个月视角评估结直肠癌手术后的生活质量(QOL)结果。
队列研究,前瞻性评估在俄斯特拉发大学医院接受择期结直肠切除术患者的术后生活质量。在固定时间点使用经过验证的简短健康调查问卷36项简表(SF-36v2™)评估生活质量。
共有148例患者纳入本研究(分别有83例和65例患者接受了腹腔镜和开放结直肠切除术)。腹腔镜组的手术时间显著更长(161分钟对133分钟;p = 0.0073),住院时间显著更短(10.7天对13.1天;p = 0.0451)。腹腔镜组的总体30天发病率较低,但差异不显著(27.7%对33.8%;p = 0.2116)。术前两个研究组的生活质量评分具有可比性(p≥0.05)。与腹腔镜手术相比,开放结直肠手术后2天和1周的生活质量在统计学上显著更低。术后1个月和6个月,两组之间无统计学显著差异。
本研究表明,腹腔镜结直肠切除术后第一个月的术后生活质量较高可能是腹腔镜手术的益处之一。