• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

母体饮食诱导的瘦素抵抗猪肥胖会改变成年后代的青春期和妊娠结局。

Maternal diet-induced obesity in swine with leptin resistance modifies puberty and pregnancy outputs of the adult offspring.

作者信息

Gonzalez-Bulnes A, Astiz S, Sanchez-Sanchez R, Perez-Solana M, Gomez-Fidalgo E

机构信息

Department of Animal Reproduction, INIA, Madrid, Spain.

出版信息

J Dev Orig Health Dis. 2013 Aug;4(4):290-5. doi: 10.1017/S2040174413000196.

DOI:10.1017/S2040174413000196
PMID:24993002
Abstract

The assessment of reproductive features (puberty, fertility and prolificacy) in female Iberian pigs indicates that exposition to intrauterine maternal malnutrition, either by deficiency or excess, is associated with juvenile obesity and a significantly earlier age of puberty onset. At adulthood, prenatal exposition to undernutrition affects reproductive outputs by diminishing prolificacy, an effect that was not found in females exposed to prenatal overnutrition.

摘要

对伊比利亚母猪生殖特征(青春期、生育能力和繁殖力)的评估表明,子宫内母体营养不良,无论是营养缺乏还是营养过剩,都与幼年肥胖以及青春期显著提前有关。成年后,产前营养不良会通过降低繁殖力来影响生殖产出,而产前营养过剩的母猪未发现这种影响。

相似文献

1
Maternal diet-induced obesity in swine with leptin resistance modifies puberty and pregnancy outputs of the adult offspring.母体饮食诱导的瘦素抵抗猪肥胖会改变成年后代的青春期和妊娠结局。
J Dev Orig Health Dis. 2013 Aug;4(4):290-5. doi: 10.1017/S2040174413000196.
2
Neonatal exposure to leptin augments diet-induced obesity in leptin-deficient Ob/Ob mice.新生期暴露于瘦素会增加瘦素缺乏的Ob/Ob小鼠因饮食诱导的肥胖。
Obesity (Silver Spring). 2008 Jun;16(6):1289-95. doi: 10.1038/oby.2008.57. Epub 2008 Mar 20.
3
Gender-specific early postnatal catch-up growth after intrauterine growth retardation by food restriction in swine with obesity/leptin resistance.宫内发育迟缓通过食物限制导致肥胖/瘦素抵抗猪的性别特异性出生后早期追赶生长。
Reproduction. 2012 Aug;144(2):269-78. doi: 10.1530/REP-12-0105. Epub 2012 Jun 12.
4
Prenatal programming in an obese swine model: sex-related effects of maternal energy restriction on morphology, metabolism and hypothalamic gene expression.肥胖猪模型中的产前编程:母体能量限制对形态、代谢和下丘脑基因表达的性别相关影响。
Br J Nutr. 2014 Feb;111(4):735-46. doi: 10.1017/S0007114513002948.
5
Ovulation rate, embryo mortality and intrauterine growth retardation in obese swine with gene polymorphisms for leptin and melanocortin receptors.肥胖猪的瘦素和黑素皮质素受体基因多态性与排卵率、胚胎死亡率和宫内生长迟缓的关系。
Theriogenology. 2011 Jan 1;75(1):34-41. doi: 10.1016/j.theriogenology.2010.07.009. Epub 2010 Sep 15.
6
Role of premature leptin surge in obesity resulting from intrauterine undernutrition.早产瘦素激增在宫内营养不良所致肥胖中的作用。
Cell Metab. 2005 Jun;1(6):371-8. doi: 10.1016/j.cmet.2005.05.005.
7
Maternal prenatal undernutrition programs adipose tissue gene expression in adult male rat offspring under high-fat diet.母体产前营养不良可调控高脂肪饮食成年雄性子代脂肪组织基因表达。
Am J Physiol Endocrinol Metab. 2011 Sep;301(3):E548-59. doi: 10.1152/ajpendo.00011.2011. Epub 2011 Jun 28.
8
Maternal overnutrition impacts offspring adiposity and brain appetite markers-modulation by postweaning diet.母体营养过剩会影响后代的肥胖和大脑食欲标志物——由断奶后饮食调节。
J Neuroendocrinol. 2010 Aug;22(8):905-14. doi: 10.1111/j.1365-2826.2010.02005.x. Epub 2010 Apr 6.
9
Maternal periconceptional undernutrition in Merinos d'Arles sheep: 1. Effects on pregnancy and reproduction results of dams and offspring growth performances.美利奴阿莱普塔羊围孕期母体营养不良:1. 对母羊妊娠和繁殖结果以及后代生长性能的影响。
Theriogenology. 2012 Apr 15;77(7):1453-65. doi: 10.1016/j.theriogenology.2011.11.015. Epub 2012 Feb 10.
10
In vitro release of ovarian progesterone is decreased during the oestrous cycle and pregnancy of swine with obesity/leptin resistance.在患有肥胖症/瘦素抵抗的母猪发情周期和怀孕期间,卵巢孕酮的体外释放减少。
Reprod Domest Anim. 2013 Jun;48(3):e44-8. doi: 10.1111/rda.12148. Epub 2013 Feb 5.

引用本文的文献

1
Association between Dietary Patterns and Precocious Puberty in Children: A Population-Based Study.儿童饮食模式与性早熟之间的关联:一项基于人群的研究。
Int J Endocrinol. 2018 Jan 16;2018:4528704. doi: 10.1155/2018/4528704. eCollection 2018.
2
Gene expression of catabolic inflammatory cytokines peak before anabolic inflammatory cytokines after ACL injury in a preclinical model.在临床前模型中,前交叉韧带损伤后,分解代谢炎症细胞因子的基因表达在合成代谢炎症细胞因子之前达到峰值。
J Inflamm (Lond). 2014 Nov 1;11(1):34. doi: 10.1186/s12950-014-0034-3. eCollection 2014.