Alsibiani Sharifa A
Department of Obstetrics and Gynecology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Gynecol Obstet Invest. 2014;78(2):88-93. doi: 10.1159/000363238. Epub 2014 Jun 28.
To investigate misoprostol use as a self-administered medical abortifacient and to explore the knowledge and availability of misoprostol and attitudes towards it among Saudi women.
A questionnaire-based cross-sectional study was conducted in obstetric and gynecological outpatient clinics at private and teaching institutions between January 1 and June 29, 2012.
Of the 678 respondents, 40% (271/678) were aware of misoprostol use as an abortifacient and 7.4% (50/678) reported personal use of it as an abortifacient. Misoprostol users were more likely to have had previous abortions (96%, 48/50; p < 0.01), had a relative/friend working in the medical field (70%, 35/50; p < 0.01) and known someone else who had used the drug (82%, 41/50; p < 0.01). The majority responded incorrectly that higher misoprostol doses are required with more advanced gestational age (96%, 48/50) and that misoprostol use confers no fetal risks (100%, 50/50).
The proportion that reported personal use of misoprostol in the current study (7.4%) exceeded that in similar samples in Brazil (2.2%) and the USA (5%). One concerning finding was the users' poor knowledge about misoprostol. Increased awareness about the inherent risks associated with unsupervised misoprostol use as an abortifacient is needed.
调查米索前列醇作为自行使用的堕胎药的使用情况，并探讨沙特女性对米索前列醇的了解程度、可得性及其态度。
于2012年1月1日至6月29日在私立和教学机构的妇产科门诊进行了一项基于问卷调查的横断面研究。
在678名受访者中，40%（271/678）知晓米索前列醇可作为堕胎药使用，7.4%（50/678）报告曾将其作为堕胎药自行使用。米索前列醇使用者更有可能既往有过堕胎经历（96%，48/50；p<0.01），有在医疗领域工作的亲属/朋友（70%，35/50；p<0.01），并且认识其他使用过该药的人（82%，41/50；p<0.01）。大多数人回答错误，认为孕周越大所需米索前列醇剂量越高（96%，48/50），且使用米索前列醇对胎儿无风险（100%，50/50）。
在本研究中报告自行使用米索前列醇的比例（7.4%）超过了巴西（2.2%）和美国（5%）类似样本中的比例。一个令人担忧的发现是使用者对米索前列醇的了解不足。需要提高对无监督使用米索前列醇作为堕胎药所固有风险的认识。
