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静脉内激光联合小切口静脉切除术治疗静脉曲张及不同激光能量水平对再通的影响:单中心经验

Endovenous laser with miniphlebectomy for treatment of varicose veins and effect of different levels of laser energy on recanalization. A single center experience.

作者信息

Golbasi Ilhan, Turkay Cengiz, Erbasan Ozan, Kemaloğlu Cemal, Sanli Suat, Turkay Mehtap, Bayezid Ömer

机构信息

Cardiovascular Surgery, Akdeniz University, Antalya, Turkey,

出版信息

Lasers Med Sci. 2015 Jan;30(1):103-8. doi: 10.1007/s10103-014-1626-0. Epub 2014 Jul 4.

DOI:10.1007/s10103-014-1626-0
PMID:24993399
Abstract

Varicose veins, associated with great saphenous vein (GSV) incompetence, are traditionally treated with conventional surgery. In recent years, minimally invasive alternatives to surgical treatment such as the endovenous laser ablation (EVLA) and radiofrequency (RF) ablation have been developed with promising results. Residual varicose veins following EVLA, regress untouched, or phlebectomy or foam sclerotherapy can be concomitantly performed. The aim of the present study was to investigate the safety and efficacy of EVLA with different levels of laser energy in patients with varicose veins secondary to saphenous vein reflux. From February 2006 to August 2011, 740 EVLA, usually with concomitant miniphlebectomies, were performed in 552 patients. A total of 665 GSV, 53 small saphenous veins (SSV), and 22 both GSV and SSV were treated with EVLA under duplex USG. At 84 patients, bilateral intervention is made. In addition, miniphlebectomy was performed in 540 patients. A duplex ultrasound (US) is performed to patients preoccupying chronic venous insufficiency (with visible varicose veins, ankle edema, skin changes, or ulcer). Saphenous vein incompetence was diagnosed with saphenofemoral, saphenopopliteal, or truncal vein reflux in response to manual compression and release with patient standing. The procedures were performed under local anesthesia with light sedation or spinal anesthesia. Endovenous 980-nm diode laser source was used at a continuous mode. The mean energy applied per length of GSV during the treatment was 77.5 ± 17.0 J (range 60-100 J/cm). An US evaluation was performed at first week of the procedure. Follow-up evaluation and duplex US scanning were performed at 1 and 6 months, and at 1 and 2 years to assess treatment efficacy and adverse reactions. Average follow-up period was 32 ± 4 months (3-55 months). There were one patient with infection and two patients with thrombus extension into the femoral vein after EVLA. Overall occlusion rate was 95%. No post-procedural deep venous thrombosis or pulmonary embolism occurred. Laser energy, less than 80 J/cm, was significantly associated with increased recanalization of saphenous vein, among the other energy levels. EVLA seems a good alternative to surgery by the application of energy of not less than 80 J/cm. It is both safe and effective. It is a well-tolerated procedure with rare and relatively minor complications.

摘要

与大隐静脉(GSV)功能不全相关的静脉曲张,传统上采用传统手术治疗。近年来,已开发出诸如腔内激光消融术(EVLA)和射频(RF)消融术等手术治疗的微创替代方法,且效果良好。EVLA术后残留的静脉曲张可任其自行消退,或可同时进行静脉切除术或泡沫硬化疗法。本研究的目的是调查不同激光能量水平的EVLA治疗大隐静脉反流继发静脉曲张患者的安全性和有效性。2006年2月至2011年8月,对552例患者进行了740次EVLA治疗,通常同时进行小静脉切除术。在双功超声引导下,共对665条大隐静脉、53条小隐静脉(SSV)以及22条大隐静脉和小隐静脉同时进行了EVLA治疗。对84例患者进行了双侧干预。此外,对540例患者进行了小静脉切除术。对患有慢性静脉功能不全(伴有可见静脉曲张、踝关节水肿、皮肤改变或溃疡)的患者进行了双功超声(US)检查。通过患者站立位时手动压迫和松开后出现的大隐股静脉、大隐腘静脉或主干静脉反流来诊断大隐静脉功能不全。手术在局部麻醉加轻度镇静或脊髓麻醉下进行。使用连续模式的980纳米腔内二极管激光源。治疗期间,大隐静脉每单位长度施加的平均能量为77.5±17.0焦耳(范围60 - 100焦耳/厘米)。在术后第一周进行了超声评估。在1个月、6个月以及1年和2年时进行随访评估和双功超声扫描,以评估治疗效果和不良反应。平均随访期为32±4个月(3 - 55个月)。EVLA术后有1例患者发生感染,2例患者血栓扩展至股静脉。总体闭塞率为95%。未发生术后深静脉血栓形成或肺栓塞。在其他能量水平中,低于80焦耳/厘米的激光能量与大隐静脉再通增加显著相关。通过应用不低于80焦耳/厘米的能量,EVLA似乎是手术的一个良好替代方法。它既安全又有效。这是一种耐受性良好的手术,并发症罕见且相对轻微。

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Endovenous ablation plus microphlebectomy/sclerotherapy for the treatment of varicose veins: single or two-stage procedure?腔内消融联合微静脉切除术/硬化疗法治疗静脉曲张:单阶段还是两阶段手术?
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Endovenous laser ablation of varicose veins with the 1470-nm diode laser.
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Use of a new endovenous laser device: results of the 1,500 nm laser.一种新型静脉内激光设备的应用:1500纳米激光的效果
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