Kontothanassis Dimitrios, Di Mitri Roberto, Ferrari Ruffino Salvatore, Zambrini Eleonora, Camporese Giuseppe, Gerard Jean Luc, Labropoulos Nicos
Istituto Flebologico Italiano, Ferrara Day Surgery, Ferrara, Italy.
J Vasc Surg. 2009 Apr;49(4):973-979.e1. doi: 10.1016/j.jvs.2008.11.019.
Endovenous laser treatment is a minimally invasive technique for ablation of the incompetent great (GSV) and small saphenous vein (SSV). Compared with the GSV, fewer data are available on SSV laser ablation and are not validated. This multicenter prospective study evaluated the feasibility, safety, and efficacy of endovenous laser ablation to treat SSVs.
Between January 2003 and January 2007, 204 patients (229 limbs) with CVD and incompetent SSVs (evaluated by the CEAP classification) who were eligible for surgery underwent consecutive laser ablation procedures. Many required additional treatment for varicose tributaries and perforator veins with phlebectomy and foam sclerotherapy, Energy was delivered to the vein wall by a 600-microm optical fiber using 810-nm or 980-nm diode laser. Ablations were performed with duplex ultrasound (DU) guidance and tumescent anesthesia. Follow-up was with clinical examination and DU imaging.
DU imaging showed immediate occlusion of the SSV with no thrombosis in the proximal veins. No complications occurred intraoperatively. All patients had postoperative ecchymosis, but it was minimal. Three patients had distal thrombotic complications. Superficial phlebitis after complementary surgery occurred in three cases. Complete occlusion with absence of flow </=2 months of follow-up was detected in 226 SSV (98.7%). It occurred 22 in patients with large SSV diameter. Recanalization was found in one patient at 12 months and in two patients at 24 months. Seven limbs had reflux in previously treated areas, treated segments, and segments in continuity with them. Three underwent an intervention to correct symptomatic reflux. The other four had no symptoms. After 1 year, eight limbs developed reflux in new locations and four underwent treatment. Symptoms resolved in most patients soon after the operation. The mean follow-up was 16 months (range, 2-39 months). After 8 to 12 months postprocedurally, the laser-treated veins were fibrotic and almost indistinguishable on DU imaging from the surrounding tissues. In five patients (2.25%) postoperative paresthesia occurred >2 to 3 days postoperatively and persisted in the follow-up. No paresthesia occurred in our last series whenever a larger amount of tumescent cold saline was infused around the vein.
Endovenous laser ablation of the SSV has excellent early and midterm results. The prevalence of thrombosis and paresthesia is very low. Symptom relief is very good.
静脉内激光治疗是一种用于消融功能不全的大隐静脉(GSV)和小隐静脉(SSV)的微创技术。与大隐静脉相比,关于小隐静脉激光消融的数据较少且未经验证。这项多中心前瞻性研究评估了静脉内激光消融治疗小隐静脉的可行性、安全性和有效性。
在2003年1月至2007年1月期间,204例患有慢性静脉疾病(CVD)且小隐静脉功能不全(通过CEAP分类评估)、符合手术条件的患者(229条肢体)接受了连续的激光消融手术。许多患者需要对曲张属支静脉和穿通静脉进行额外的静脉切除术和泡沫硬化疗法治疗。通过一根600微米的光纤,使用810纳米或980纳米的二极管激光将能量传递至静脉壁。在双功超声(DU)引导和肿胀麻醉下进行消融。通过临床检查和DU成像进行随访。
DU成像显示小隐静脉立即闭塞,近端静脉无血栓形成。术中未发生并发症。所有患者术后均有瘀斑,但程度轻微。3例患者出现远端血栓形成并发症。辅助手术后发生浅静脉炎3例。在226条小隐静脉(98.7%)中检测到在随访≤2个月时完全闭塞且无血流。在小隐静脉直径较大的患者中发生22例。1例患者在12个月时发现再通,2例患者在24个月时发现再通。7条肢体在先前治疗区域、治疗段及其连续段存在反流。3例接受了干预以纠正有症状的反流。另外4例无症状。1年后,8条肢体在新部位出现反流,4例接受了治疗。大多数患者术后症状很快缓解。平均随访16个月(范围2 - 39个月)。在术后8至12个月,激光治疗的静脉发生纤维化,在DU成像上与周围组织几乎无法区分。5例患者(2.25%)术后感觉异常在术后>2至3天出现,并在随访中持续存在。在我们最后一组病例中,每当在静脉周围注入大量肿胀冷盐水时,未发生感觉异常。
小隐静脉的静脉内激光消融具有优异的早期和中期效果。血栓形成和感觉异常的发生率非常低。症状缓解非常好。