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舟状骨骨折:临床试验的高阶分析及临床推理策略的应用

Scaphoid fractures: a higher order analysis of clinical tests and application of clinical reasoning strategies.

作者信息

Burrows Blayne, Moreira Paula, Murphy Chris, Sadi Jackie, Walton David M

机构信息

Western University, School of Physical Therapy, MClSc (Manipulative Therapy Field), Canada.

Western University, School of Physical Therapy, MClSc (Manipulative Therapy Field), Canada.

出版信息

Man Ther. 2014 Oct;19(5):372-8. doi: 10.1016/j.math.2014.05.007. Epub 2014 Jun 9.

Abstract

INTRODUCTION

The purpose of this study was to identify clinical tests for scaphoid fractures and, using a higher order analysis, to determine their diagnostic accuracy.

METHODS

A literature review of the databases CINAHL, Embase, Medline and PUBMED from 1980 to September 30, 2011 was conducted to obtain applicable literature on clinical tests used in identifying scaphoid fractures. Methodological quality was determined using the criteria for validity suggested by Sackett et al (2000). Using a random effects model, pooled positive likelihood ratios (PPLR) were established for any test evaluated in at least 3 published studies. Moderator analyses provided insight into heterogeneity of results.

RESULTS

Higher order analysis indicated that the scaphoid compression test, anatomical snuffbox tenderness and scaphoid tubercle tenderness demonstrated statistically significant ability to identify scaphoid fractures with PPLR of 2.37 (1.27-4.41), 1.52 (1.12-2.06) and 1.67 (1.33-2.09) respectively. Descriptive factors (gender and mechanism of injury) were also identified but did not demonstrate significant diagnostic ability. Pooled data revealed the existence of heterogeneity for the three clinical tests and descriptive factors, which could not be easily explained.

CONCLUSION

Three clinical tests with statistically significant diagnostic validity were identified. In isolation, the clinical significance of each is questionable. Further studies with description of sample characteristics, blinded assessments, and agreement on a reference standard are recommended.

摘要

引言

本研究的目的是确定用于诊断舟状骨骨折的临床检查方法,并通过高阶分析来确定其诊断准确性。

方法

对1980年至2011年9月30日期间的CINAHL、Embase、Medline和PUBMED数据库进行文献综述,以获取有关用于诊断舟状骨骨折的临床检查方法的适用文献。使用Sackett等人(2000年)提出的有效性标准来确定方法学质量。采用随机效应模型,为至少在3篇已发表研究中评估的任何检查方法建立合并阳性似然比(PPLR)。调节因素分析有助于深入了解结果的异质性。

结果

高阶分析表明,舟状骨挤压试验、解剖学鼻烟壶压痛和舟状骨结节压痛在识别舟状骨骨折方面具有统计学意义的能力,其PPLR分别为2.37(1.27 - 4.41)、1.52(1.12 - 2.06)和1.67(1.33 - 2.09)。还确定了描述性因素(性别和损伤机制),但未显示出显著的诊断能力。汇总数据显示这三种临床检查方法和描述性因素存在异质性,难以轻易解释。

结论

确定了三种具有统计学显著诊断有效性的临床检查方法。单独来看,每种方法的临床意义都值得怀疑。建议进一步开展研究,描述样本特征、采用盲法评估并就参考标准达成一致。

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