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法国国家阿尔茨海默病数据库:一个为研究人员和临床医生快速增长的数据库。

The French National Alzheimer database: a fast growing database for researchers and clinicians.

作者信息

Anthony Sabine, Pradier Christian, Chevrier Roland, Festraëts Julie, Tifratene Karim, Robert Philippe

机构信息

Department of Public Health, Nice University Hospital, Nice, France.

出版信息

Dement Geriatr Cogn Disord. 2014;38(5-6):271-80. doi: 10.1159/000360281. Epub 2014 Jul 2.

Abstract

BACKGROUND

Alzheimer's disease (AD) is a major public health issue. The French National Alzheimer database (BNA) registers all medical acts performed by memory units and independent specialists throughout France. This article describes the national coverage, the registered patient characteristics and illustrates research possibilities.

METHODS

All data transmitted up to December 2012 were analyzed. The following patient characteristics were studied: age, sex, educational level, place of living, diagnosis, Mini-Mental State Examination score and existence of pharmacological or psychosocial interventions.

RESULTS

At the end of 2012, the BNA included 84% (n = 357) of all French memory units, contained 341,498 patients and more than 800,000 medical acts. AD accounted for 26.4% of all registered diagnoses, related disorders for 21.7% and mild cognitive impairment for 8.7%.

CONCLUSION

The BNA offers a multitude of research possibilities. In the coming years, the BNA will play a major role in monitoring trends and related risk factors in AD.

摘要

背景

阿尔茨海默病(AD)是一个重大的公共卫生问题。法国国家阿尔茨海默病数据库(BNA)记录了法国各地记忆单元和独立专家所实施的所有医疗行为。本文描述了全国范围的覆盖情况、登记患者的特征,并展示了研究可能性。

方法

对截至2012年12月传输的所有数据进行分析。研究了以下患者特征:年龄、性别、教育水平、居住地点、诊断、简易精神状态检查表评分以及是否存在药物或心理社会干预措施。

结果

到2012年底,BNA涵盖了法国所有记忆单元的84%(n = 357),包含341498名患者以及超过800000次医疗行为。AD占所有登记诊断的26.4%,相关疾病占21.7%,轻度认知障碍占8.7%。

结论

BNA提供了众多研究可能性。在未来几年,BNA将在监测AD的趋势和相关风险因素方面发挥重要作用。

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