Miller S, Jungheim M, Schwemmle C, Schoof S, Ptok M
Klinik und Poliklinik für Phoniatrie und Pädaudiologie, Medizinische Hochschule Hannover, Hannover.
Klinik für Pädiatrische Kardiologie und Intensivmedzin, Medizinische Hochschule Hannover, Hannover.
Laryngorhinootologie. 2014 Oct;93(10):677-81. doi: 10.1055/s-0034-1375659. Epub 2014 Jul 7.
Inducible Laryngeal Obstruction vs. Bronchial -Asthma Background: Inducible laryngeal obstructions (ILO) represent paroxysmal and sometimes severe dyspnea caused by different factors. Symptomatically ILO resembles bronchial asthma and is therefore often misdiagnosed. In the following 3 cases regarding a special type of ILO, the exercise induced laryngeal obstruction (EILO) will be presented. It will also be demonstrated, how EILO can be diagnosed and differentiated from bronchial asthma.
Laryngeal symptoms were provoked by spiroergometry (treadmill or bicycle) and inspected by laryngoscopy.
Symptoms could be provoked in all of the 3 patients by either treadmill or bicycle spiroergometry. When a stridor occurred, usually 1.5-2 min after the anaerobe threshold had been exceeded, spiroergometry showed a decline or plateau of carbon dioxide emission and oxygen intake. Laryngoscopy revealed adduction of the vocal cords during inspiration occa-sionally with a collapse of supraglottic structures towards the endolarynx.
This article is the first to report that EILO can be distinctly depicted by spiroergometry. The decline or plateau in oxygen and carbon dioxide curves in coordination with the onset of stridor, approximately 1.5-2 min after the anaerobe threshold had been exceeded, was found to be reproducible in all cases. Furthermore, endoscopy immediately following peak exhaustion represents a practical tool for the identification of EILO.·
可诱导性喉梗阻与支气管哮喘
可诱导性喉梗阻(ILO)表现为由不同因素引起的阵发性且有时严重的呼吸困难。在症状上,ILO类似于支气管哮喘,因此常被误诊。在以下3例关于一种特殊类型的ILO,即运动诱发性喉梗阻(EILO)的病例中,将对其进行介绍。还将展示如何诊断EILO并将其与支气管哮喘相鉴别。
通过运动心肺功能测试(跑步机或自行车)诱发喉部症状,并通过喉镜检查。
3例患者通过跑步机或自行车运动心肺功能测试均可诱发症状。当出现喘鸣时,通常在超过无氧阈值后1.5 - 2分钟,运动心肺功能测试显示二氧化碳排放和氧气摄取下降或达到平台期。喉镜检查显示吸气时声带内收,有时声门上结构向喉内塌陷。
本文首次报道运动心肺功能测试可清晰描绘EILO。发现无氧阈值超过后约1.5 - 2分钟,氧气和二氧化碳曲线的下降或平台期与喘鸣发作同步,在所有病例中均可重现。此外,力竭峰值后立即进行的内镜检查是识别EILO的实用工具。