Koh Jaehan, Chaudhary Vipin, Jeon Eun Kyung, Dhillon Gurmeet
Department of Computer Science and Engineering, State University of New York at Buffalo, Buffalo, NY 14228, USA.
Department of Chemistry, State University of New York at Buffalo, Buffalo, NY 14260, USA.
Comput Med Imaging Graph. 2014 Oct;38(7):569-79. doi: 10.1016/j.compmedimag.2014.06.003. Epub 2014 Jun 18.
As there is an increasing need for the computer-aided effective management of pathology in lumbar spine, we have developed a computer-aided diagnosis and characterization framework using lumbar spine MRI that provides radiologists a second opinion. In this paper, we propose a left spinal canal boundary extraction method, based on dynamic programming in lumbar spine MRI. Our method fuses the absolute intensity difference of T1-weighted and T2-weighted sagittal images and the inverted gradient of the difference image into a dynamic programming scheme and works in a fully automatic fashion. The boundaries generated by our method are compared against reference boundaries in terms of the Euclidean distance and the Chebyshev distance. The experimental results from 85 clinical data show that our methods find the boundary with a mean Euclidean distance of 3mm, achieving a speedup factor of 167 compared with manual landmark extraction. The proposed method successfully extracts landmarks automatically and fits well with our framework for computer-aided diagnosis in lumbar spine.
由于对腰椎病理学进行计算机辅助有效管理的需求日益增加,我们开发了一种使用腰椎磁共振成像(MRI)的计算机辅助诊断和特征描述框架,为放射科医生提供第二种意见。在本文中,我们提出了一种基于动态规划的腰椎MRI左椎管边界提取方法。我们的方法将T1加权和T2加权矢状图像的绝对强度差异以及差异图像的反转梯度融合到一个动态规划方案中,并以全自动方式运行。我们方法生成的边界与参考边界在欧几里得距离和切比雪夫距离方面进行了比较。来自85个临床数据的实验结果表明,我们的方法找到的边界的平均欧几里得距离为3毫米,与手动地标提取相比,加速因子达到167。所提出的方法成功地自动提取了地标,并且与我们的腰椎计算机辅助诊断框架非常契合。