Długoń E, Niemiec W, Frączek-Szczypta A, Jeleń P, Sitarz M, Błażewicz M
Faculty of Materials Science and Ceramics, AGH University of Science and Technology, al. Mickiewicza 30, 30-059 Krakow, Poland.
Faculty of Materials Science and Ceramics, AGH University of Science and Technology, al. Mickiewicza 30, 30-059 Krakow, Poland.
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Dec 10;133:872-5. doi: 10.1016/j.saa.2014.06.064. Epub 2014 Jun 18.
Carbon nanotubes deposited on the surface of the metal can be used in a wide variety of applications for modern medicine including: sensors and sensor array devices, electrodes for neural system stimulation, scaffolds for improved healing process for bone defects. Additionally it is debated if deposited on the surface of e.g. endoprosthesis, CNT coating can significantly increase the strength of the tissue/bone joint and stimulate a fast integration of the implant and the tissue. The aim of this paper is the analysis of the electrophoretically deposited nanocomposite coating made of hydroxyapatite nanoparticles and carbon nanotubes on the surface of titanium. The paper concentrates on the analysis of the layer's structure and its bioactivity properties. The nanocomposite films were investigated using Raman Spectroscopy as well as AFM and SEM microscopy. The measurements were conducted at every stage of layer preparation and after bioactivity test. Bioactivity was evaluated by in vitro test in Simulated Body Fluid (SBF, 37°C, for 30days). It was shown that hybrid HAp/CNT layers are very attractive materials for modification of the surface of metallic orthopedic implants.
沉积在金属表面的碳纳米管可用于现代医学的多种应用，包括：传感器和传感器阵列设备、用于神经系统刺激的电极、用于改善骨缺损愈合过程的支架。此外，对于例如沉积在内植物表面的碳纳米管涂层是否能显著提高组织/骨结合强度并促进植入物与组织的快速整合，仍存在争议。本文的目的是分析在钛表面电泳沉积的由羟基磷灰石纳米颗粒和碳纳米管制成的纳米复合涂层。本文着重分析该涂层的结构及其生物活性特性。使用拉曼光谱以及原子力显微镜和扫描电子显微镜对纳米复合薄膜进行了研究。在涂层制备的每个阶段以及生物活性测试后都进行了测量。通过在模拟体液（SBF，37°C，30天）中进行体外测试来评估生物活性。结果表明，HAp/CNT混合涂层是用于金属骨科植入物表面改性的非常有吸引力的材料。
