Sayegh Eli T, Strauch Robert J
Department of Orthopaedic Surgery, Columbia University Medical Center, New York, NY.
Department of Orthopaedic Surgery, Columbia University Medical Center, New York, NY.
J Hand Surg Am. 2014 Aug;39(8):1500-6.e7. doi: 10.1016/j.jhsa.2014.05.009. Epub 2014 Jul 3.
To systematically compare outcomes between corticocancellous (CC) and cancellous-only (C-only) bone grafts for unstable scaphoid nonunions.
The English-language literature was searched using PubMed, the Cumulative Index to Nursing and Allied Health Literature, and the Cochrane Library with the following keywords: scaphoid, nonunion, malunion, unstable, collapse, humpback, dorsal intercalated segment instability, and deformity. Studies whose patient populations were characterized as possessing unstable scaphoid nonunion and/or collapse deformity or who met radiological definitions of such deformity were included. The union rate, interval to union, clinical assessments, strength, range of motion, correction of deformity, pain, and return to activity were analyzed.
Twenty-three studies published between the beginning of 1987 and the end of 2013 met the eligibility criteria and contained 604 patients. The union rate was statistically equivalent for C-only (95%) and CC grafts (92%). However, the frequency-weighted mean interval to union was significantly shorter for C-only (11 wk) than for CC grafts (16 wk). CC grafts were associated with a significantly higher frequency-weighted mean Mayo wrist score (86) than C-only grafts (80), whereas C-only grafting provided significantly greater improvement of wrist flexion. Of the 3 measures of carpal geometry analyzed, CC grafts significantly improved the scapholunate and radiolunate angles more than C-only grafts.
Based on retrospective data from uncontrolled studies, C-only grafts provide the shortest interval to union for unstable scaphoid nonunions. CC grafts are associated with consistent deformity correction and superior Mayo wrist scores.
TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.
系统比较皮质松质骨(CC)移植和单纯松质骨(仅C)移植治疗不稳定舟骨不愈合的疗效。
使用PubMed、护理及相关健康文献累积索引和Cochrane图书馆,以舟骨、不愈合、畸形愈合、不稳定、塌陷、驼背、背侧插入节段不稳定和畸形等关键词检索英文文献。纳入患者人群具有不稳定舟骨不愈合和/或塌陷畸形特征或符合此类畸形放射学定义的研究。分析愈合率、愈合间隔、临床评估、强度、活动范围、畸形矫正、疼痛和恢复活动情况。
1987年初至2013年底发表的23项研究符合纳入标准,共纳入604例患者。仅C移植(95%)和CC移植(92%)的愈合率在统计学上相当。然而,仅C移植的频率加权平均愈合间隔(11周)明显短于CC移植(16周)。CC移植的频率加权平均Mayo腕关节评分(86分)明显高于仅C移植(80分),而仅C移植在腕关节屈曲方面的改善明显更大。在分析的3项腕骨几何测量指标中,CC移植比仅C移植更能显著改善舟月角和桡月角。
基于非对照研究的回顾性数据,仅C移植治疗不稳定舟骨不愈合的愈合间隔最短。CC移植与持续的畸形矫正和更高的Mayo腕关节评分相关。
研究类型/证据水平:治疗性IV级。