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室间隔缺损修复术后的心律失常疾病。心房和心室入路的比较

[Arrhythmia disorders after repair of ventricular septal defects. Comparison of atrial and ventricular approaches].

作者信息

Vaksmann G, Fournier A, Chartrand C, Stanley P, Davignon A

机构信息

Services de cardiologie et de chirurgie cardiaque, Hôpital Sainte-Justine, côte Sainte-Catherine, Montréal, Québec.

出版信息

Arch Mal Coeur Vaiss. 1989 May;82(5):731-5.

PMID:2500097
Abstract

Post-operative disorders of conduction and of ventricular and supraventricular excitability were studied in 50 patients operated upon for ventricular septal defect (VSD). The VSD was approached by right ventriculotomy in 29 patients aged 4.4 +/- 3.1 years at surgery and 15.1 +/- 6.5 years at evaluation. The VSD was closed by the atrial route in 21 patients aged 6.6 +/- 3.9 years at surgery and 12.1 +/- 6.8 years at evaluation. Complete right bundle branch block (CRBB) was significantly more frequent in patients who underwent ventriculotomy (62 p. 100 vs 33 p. 100, p less than 0.05), but 2 late complete atrioventricular blocks were observed in patients in whom the atrial route was used. 34 p. 100 of the patients with ventriculotomy and 26.5 p. 100 of those without ventriculotomy had significant ventricular arrhythmias on Holter recordings (greater than or equal to Lown's grade 2, p = NS). The occurrence of ventricular arrhythmias in the patient population as a whole increased significantly with age at surgery and age at evaluation (p less than 0.05); this increase was also noted in each group (p = 0.06). Pre-operative right ventricular systolic pressure, severity of intraventricular disorders of conduction or duration of extracorporeal circulation and aortic clamping had no influence on the occurrence of ventricular arrhythmias. Disorders of supraventricular excitability were found in 1 patient who had ventriculotomy and in 2 patients whose VSD was corrected by the atrial route. No sinus dysfunction was observed. It is concluded that the ventricular approach of VSD significantly increases the occurrence of post-operative CRBB.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对50例接受室间隔缺损(VSD)手术的患者进行了术后传导障碍以及心室和室上性兴奋性障碍的研究。29例患者通过右心室切开术治疗VSD,手术时年龄为4.4±3.1岁,评估时年龄为15.1±6.5岁。21例患者通过心房途径闭合VSD,手术时年龄为6.6±3.9岁,评估时年龄为12.1±6.8岁。接受心室切开术的患者中完全性右束支传导阻滞(CRBB)的发生率显著更高(62%对33%,p<0.05),但在采用心房途径的患者中观察到2例晚期完全性房室传导阻滞。接受心室切开术的患者中有34%、未接受心室切开术的患者中有26.5%在动态心电图记录上有明显的室性心律失常(≥洛恩分级2级,p=无显著性差异)。总体患者人群中室性心律失常的发生率随手术时年龄和评估时年龄显著增加(p<0.05);每组中也有这种增加(p=0.06)。术前右心室收缩压、心室内传导障碍的严重程度、体外循环和主动脉阻断的持续时间对室性心律失常的发生没有影响。在1例接受心室切开术的患者和2例通过心房途径纠正VSD的患者中发现了室上性兴奋性障碍。未观察到窦性功能障碍。结论是,VSD的心室入路显著增加了术后CRBB的发生率。(摘要截短至250字)

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